News & Events

Cambridge, MA, February 23, 2006- Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) will webcast its corporate presentation at the Citigroup 2006 Healthcare Conference in Washington, DC. The presentation will be delivered by Joshua Boger, Ph.D., Vertex's Chairman, President and Chief Executive Officer, on Monday, February 27, 2006, at 11:30 a.m. EST.

The presentation will be webcast live and may be accessed by visiting Vertex's website at www.vrtx.com. A replay of the webcast will also be available on the Company's website until March 6, 2006. To access the webcast, go to Vertex's website and select 'Citigroup 2006 Healthcare Conference.' To ensure a timely connection to the webcast, it is recommended that users register at least 15 minutes prior to the scheduled webcast.

About Vertex

Vertex Pharmaceuticals Incorporated is a global biotechnology company committed to the discovery and development of breakthrough small molecule drugs for serious diseases. The Company's strategy is to commercialize its products both independently and in collaboration with major pharmaceutical companies. Vertex's product pipeline is principally focused on viral diseases, inflammation, autoimmune diseases and cancer. Vertex co-promotes the HIV protease inhibitor, Lexiva, with GlaxoSmithKline.

Lexiva is a registered trademark of the GlaxoSmithKline group of companies.

Vertex Contact:
Lora Pike, Manager, Investor Relations, (617) 444-6755