Institutional Investors and Financial Analysts, please contact:

Main email: investorinfo@vrtx.com
Main phone: 617-961-7163

Michael Partridge
Senior Vice President, Investor Relations
617.341.6108

Eric Rojas
Senior Director, Investor Relations
617.961.7205

Zach Barber
Senior Director, Investor Relations
617.341.6470

Leah Gibson
Associate Director, Investor Relations
617.961.1507

Contact Vertex's Transfer Agent
Communication regarding transfer requirements, lost certificates and changes of address should be directed to: