Stock Appreciation Rights (SARs) Stock Appreciation Rights (SARs) [Member] Schedule of Stock Options Outstanding and Exercisable Share-Based Payment Arrangement, Option, Exercise Price Range [Table Text Block] Schedule of Accrued Expenses Schedule of Accrued Liabilities [Table Text Block] Accrued expenses Total Accrued Liabilities, Current Other long-term liabilities Other Noncurrent Liabilities [Member] Line of credit facility, maximum borrowing capacity Line of Credit Facility, Maximum Borrowing Capacity Research and development expenses Research and Development Expense Changes in operating assets and liabilities: Increase (Decrease) in Operating Capital [Abstract] Expiration period Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period Schedule of Revenues by Product Revenue from External Customers by Products and Services [Table Text Block] Award Type [Domain] Award Type [Domain] Fair Value as of Grant Date Award Grant Date Fair Value Acquired in-process research and development expenses Research and Development Asset Acquired Other than Through Business Combination, Writeoff Property and equipment, net Finance Lease, Right-Of-Use Asset, Gross Finance Lease, Right-Of-Use Asset, Gross Foreign derived intangible income deduction Effective Income Tax Rate Reconciliation, FDII, Percent Prepaid expenses and other current assets Prepaid Expenses and Other Current Assets [Member] Stock compensation (benefit), shortfalls and cancellations Effective Income Tax Rate Reconciliation, Nondeductible Expense, Share-Based Payment Arrangement, Percent Collaborative arrangement, allocation of research and development expenses, percent Collaborative Arrangement, Allocation Of Research And Development Expenses, Percent Collaborative Arrangement, Allocation Of Research And Development Expenses, Percent Insider Trading Policies and Procedures [Line Items] Exercisable (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number Rule 10b5-1 Arrangement Terminated Rule 10b5-1 Arrangement Terminated [Flag] Derivative asset current, foreign currency forward contracts Derivative Asset, Current 2028 Lessee, Operating Lease, Liability, to be Paid, Year Five Restatement does not require Recovery Restatement Does Not Require Recovery [Text Block] Schedule of Revenues and Property and Equipment by Location Schedule of Revenue from External Customers and Long-Lived Assets, by Geographical Areas [Table Text Block] Accrued expenses Accrued Liabilities, Current [Abstract] Line of Credit Facility [Line Items] Line of Credit Facility [Line Items] Impairment, Intangible Asset, Indefinite-Lived (Excluding Goodwill), Statement of Income or Comprehensive Income [Extensible Enumeration] Impairment, Intangible Asset, Indefinite-Lived (Excluding Goodwill), Statement of Income or Comprehensive Income [Extensible Enumeration] Canadian dollar Canada, Dollars Total financial liabilities Financial Liabilities Fair Value Disclosure Customer [Axis] Customer [Axis] Current liabilities: Liabilities, Current [Abstract] Federal Deferred Federal Income Tax Expense (Benefit) Preferred stock, $0.01 par value; 1,000,000 shares authorized; none issued and outstanding Preferred Stock, Value, Issued Subsequent Event Type [Domain] Subsequent Event Type [Domain] Derivative Instruments, Gain (Loss) [Line Items] Derivative Instruments, Gain (Loss) [Line Items] Diluted (in dollars per share) Diluted net income per common share (in dollars per share) Earnings Per Share, Diluted Net unrealized (losses) gains Unrealized Gain (Loss) on Investments In-process Research and Development Assets / Finite-lived Intangible Assets Goodwill and Intangible Assets, Intangible Assets, Policy [Policy Text Block] Accounts receivable, net Accounts Receivable, after Allowance for Credit Loss, Current Collaborative Arrangements by Agreement [Domain] Collaborative Arrangements by Agreement [Domain] Collaborative Arrangements by Agreement [Domain] Potential awards, percent of target shares, maximum Share-Based Compensation By Share-Based Payment Award, Award Percentage Of Target, Maximum Share-Based Compensation By Share-Based Payment Award, Award Percentage Of Target, Maximum Unrealized (losses) gains on foreign currency forward contracts, net of tax of $14.0, $1.0 and $(21.8), respectively Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), after Reclassification and Tax, Parent Trading Symbol Trading Symbol Granted (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Collaborative Arrangement and Arrangement Other than Collaborative [Table] Collaborative Arrangement and Arrangement Other than Collaborative [Table] Unrealized holding gains (losses) on marketable securities, tax OCI, Debt Securities, Available-for-Sale, Gain (Loss), after Adjustment, Tax Fair Value Disclosures [Abstract] Fair Value Disclosures [Abstract] Indefinite-lived Intangible Assets, Major Class Name [Domain] Indefinite-Lived Intangible Assets, Major Class Name [Domain] Intangible assets, gross (excluding goodwill) Intangible Assets, Gross (Excluding Goodwill) All Currencies [Domain] All Currencies [Domain] ESPP share issuances Employee Stock [Member] Tax rate change Effective Income Tax Rate Reconciliation, Change in Enacted Tax Rate, Percent Contract liabilities Contract with Customer, Liability Schedule of Earnings Per Share, Basic and Diluted Schedule of Earnings Per Share, Basic and Diluted [Table Text Block] 2027 Finance Lease And Operating Lease, Liability, Payments, Due Year Four Finance Lease And Operating Lease, Liability, Payments, Due Year Four Executive Category: Executive Category [Axis] Number of Shares Number of Units Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward] Financial instruments carried at fair value (liability positions): Financial Liabilities Fair Value Disclosure [Abstract] Exercised (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Level 1 Fair Value, Inputs, Level 1 [Member] Total deferred tax assets Deferred Tax Assets, Net of Valuation Allowance Marketable securities Marketable Securities, Current British pound sterling United Kingdom, Pounds Schedule of Property and Equipment Property, Plant and Equipment [Table Text Block] Equity Components [Axis] Equity Components [Axis] Financial Instruments [Domain] Financial Instruments [Domain] Additional 402(v) Disclosure Additional 402(v) Disclosure [Text Block] Hedging Relationship [Domain] Hedging Relationship [Domain] Certificates of deposit Certificates of Deposit [Member] Collaborative arrangement, option payment Collaborative Arrangement, Option Payment Collaborative Arrangement, Option Payment Additional awards authorized for grant (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant Granted (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross Entity Small Business Entity Small Business 2027 Finite-Lived Intangible Asset, Expected Amortization, Year Four Local Phone Number Local Phone Number Recovery of Erroneously Awarded Compensation Disclosure [Line Items] Letter of Credit Letter of Credit [Member] 2028 Finance Lease, Liability, to be Paid, Year Five Verve Verve [Member] Verve Percent of Accounts Receivable Accounts Receivable [Member] Notional amount of foreign currency forward contract Derivative, Notional Amount Fair Value by Measurement Frequency [Axis] Measurement Frequency [Axis] Restricted stock units (including PSUs) Unvested restricted stock units (including PSUs) Restricted Stock Units (excluding PSUs) Restricted Stock Units (RSUs) [Member] Schedule of Restricted Stock and Restricted Stock Units Activity Share-Based Payment Arrangement, Restricted Stock and Restricted Stock Unit, Activity [Table Text Block] Forgone Recovery due to Violation of Home Country Law, Amount Forgone Recovery due to Violation of Home Country Law, Amount Operating leases Leases, Operating [Abstract] Depreciation expense Depreciation ApolLo1 Bio, LLC ApolLo1 Bio, LLC [Member] ApolLo1 Bio, LLC Other Other Sundry Liabilities, Noncurrent Line of Credit Facility [Table] Line of Credit Facility [Table] Research and development expenses Research and Development Expense (Excluding Acquired in Process Cost) License agreement, upfront payment reimbursement License Agreement, Upfront Payment Reimbursement License Agreement, Upfront Payment Reimbursement Common stock withheld for employee tax obligations Share-Based Payment Arrangement, Decrease for Tax Withholding Obligation Walgreen Co. Walgreen Co. [Member] Walgreen Co. [Member] Non-financial performance shares Non-Financial Performance Shares [Member] Non-Financial Performance Shares Variable Interest Entities Consolidation, Variable Interest Entity, Policy [Policy Text Block] SYMDEKO/SYMKEVI SYMDEKO/SYMKEVI [Member] SYMDEKO/SYMKEVI [Member] Schedule of Potential Gross Common Equivalent Shares Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Options outstanding and exercisable, number outstanding (in shares) Share-Based Payment Arrangement, Option, Exercise Price Range, Shares Outstanding Aggregate Available Trading Arrangement, Securities Aggregate Available Amount Research and development expenses Research and Development Expense [Member] Insider Trading Policies and Procedures Not Adopted Insider Trading Policies and Procedures Not Adopted [Text Block] Collaborative arrangement, reimbursement of upfront payment, percent Collaborative Arrangement, Reimbursement Of Upfront Payment, Percent Collaborative Arrangement, Reimbursement Of Upfront Payment, Percent Antidilutive securities excluded from computation of earnings per share (in shares) Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Award Type [Axis] Award Type [Axis] Granted (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period Reconciliation of Unrecognized Tax Benefits, Excluding Amounts Pertaining to Examined Tax Returns [Roll Forward] Reconciliation of Unrecognized Tax Benefits, Excluding Amounts Pertaining to Examined Tax Returns [Roll Forward] Fair Value, Measurements, Fair Value Hierarchy [Domain] Fair Value Hierarchy and NAV [Domain] ICFR Auditor Attestation Flag ICFR Auditor Attestation Flag Hedging Designation [Axis] Hedging Designation [Axis] Operating leases Right-of-Use Asset Obtained in Exchange for Operating Lease Liability Less: amount representing interest Lessee, Operating Lease, Liability, Undiscounted Excess Amount PEO Actually Paid Compensation Amount PEO Actually Paid Compensation Amount Leases Lessee, Finance Leases [Text Block] Schedule of Components of Provision for (Benefit From) Income Taxes Schedule of Components of Income Tax Expense (Benefit) [Table Text Block] Stock-based compensation expense: Share-based Compensation Allocation [Abstract] -- None. No documentation exists for this element. -- Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table] Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table] Amortized Cost Cash Equivalents And Debt Securities, Available for Sale Cash Equivalents And Debt Securities, Available for Sale Total liabilities Offsetting Derivative Liabilities [Abstract] Operating lease liabilities Other current liabilities Operating Lease, Liability, Current Prepaid expenses Prepaid Expense, Current Interest on lease liabilities Finance Lease, Interest Expense Computers and software Computer Software, Intangible Asset [Member] Sales and maturities of available-for-sale debt securities Proceeds from Sale and Maturity of Debt Securities, Available-for-Sale 2026 Lessee, Operating Lease, Liability, to be Paid, Year Three Foreign currency translation adjustment Unrecognized Tax Benefits, Decrease Resulting from Foreign Currency Translation Other comprehensive income (loss) income before reclassifications OCI, before Reclassifications, Net of Tax, Attributable to Parent Finite-lived intangible assets, net, total Finite-Lived Intangible Assets, Net Property, Plant and Equipment [Line Items] Property, Plant and Equipment [Line Items] Recently Adopted and Issued Accounting Standards New Accounting Pronouncements, Policy [Policy Text Block] Schedule of Offsetting Liabilities Offsetting Liabilities [Table Text Block] Accumulated Amortization Finite-Lived Intangible Assets, Accumulated Amortization 2025 Lessee, Operating Lease, Liability, to be Paid, Year Two Number of approved gene therapy medicines Number of Approved Gene Therapy Medicines Number of approved gene therapy medicines Schedule of Components of Income Before Provision for (Benefit From) Income Taxes Schedule of Income before Income Tax, Domestic and Foreign [Table Text Block] Government-sponsored enterprise securities Government-sponsored enterprise securities US Government-sponsored Enterprises Debt Securities [Member] Stock Price or TSR Estimation Method Stock Price or TSR Estimation Method [Text Block] Foreign Income (Loss) from Continuing Operations before Income Taxes, Foreign Security Exchange Name Security Exchange Name Selling, general and administrative expenses Selling, General and Administrative Expense Accumulated other comprehensive (loss) income Accumulated Other Comprehensive Income (Loss), Net of Tax Swiss Franc Switzerland, Francs Vesting percentage Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Rights, Percentage Collaboration, License and Other Arrangements Collaborative Arrangement Disclosure [Text Block] Stock options Stock options Stock options Employee Stock Option [Member] Hedging Derivative Instruments and Hedging Activities Disclosure [Text Block] Uncertain tax positions Effective Income Tax Rate Reconciliation, Uncertain Tax Positions, Percent Effective Income Tax Rate Reconciliation, Uncertain Tax Positions, Percent Gross Amounts Not Offset Derivative Liability, Subject to Master Netting Arrangement, Deduction of Financial Instrument Not Offset Legal Offset Derivative Liability, Fair Value, Offset Against Collateral, Net of Not Subject to Master Netting Arrangement, Policy Election Collaborative arrangement development and regulatory potential milestone payments maximum Collaborative Arrangement Development And Regulatory Potential Milestone Payments Maximum Represents the potential milestone amount to be paid by the entity under the collaboration agreement if drug candidates are approved and commercialized. Total costs and expenses Costs and Expenses Maximum Maximum [Member] Unrecognized Expense Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount Document Type Document Type Tabular List, Table Tabular List [Table Text Block] Operating loss carryforwards, subject to expiration Deferred Tax Assets, Operating Loss Carryforwards, Subject to Expiration Long-term marketable securities Marketable Securities, Noncurrent Inventories Inventory, Policy [Policy Text Block] Percentage of employees eligible for acceleration of equity awards (less than) (percent) Percentage of employees eligible for acceleration of equity awards Percentage of employees eligible for acceleration of equity awards Number of optional renewal terms Lessee, Operating Lease, Number Of Renewal Options Lessee, Operating Lease, Number Of Renewal Options 2026 Finance Lease, Liability, to be Paid, Year Three Antidilutive Securities, Name [Domain] Antidilutive Securities, Name [Domain] Other current liabilities, foreign currency forward contracts Derivative Liability, Current Stock-based Compensation Expense Share-Based Payment Arrangement [Text Block] Federal Current Federal Tax Expense (Benefit) Basis of Presentation Basis of Accounting, Policy [Policy Text Block] Other non-cash items, net Other Noncash Income (Expense) Purchases of available-for-sale debt securities Payments to Acquire Debt Securities, Available-for-Sale Financial performance shares Financial Performance Shares [Member] Financial Performance Shares Gross Unrealized Losses Equity Securities, FV-NI, Unrealized Loss Derivative [Table] Derivative [Table] State Deferred State and Local Income Tax Expense (Benefit) Variable Rate [Axis] Variable Rate [Axis] Raw materials Inventory, Raw Materials, Net of Reserves Costs and expenses: Costs and Expenses [Abstract] Forfeited (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period Title of 12(b) Security Title of 12(b) Security Sublease income Sublease Income Share Repurchase Programs Stockholders' Equity, Policy [Policy Text Block] Indefinite-lived intangible assets (excluding goodwill) Indefinite-Lived Intangible Assets (Excluding Goodwill) Aggregate Erroneous Compensation Not Yet Determined Aggregate Erroneous Compensation Not Yet Determined [Text Block] Beginning of the period (in dollars per share) End of the period (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value Income Tax Disclosure [Abstract] Income Tax Disclosure [Abstract] Forgone Recovery due to Expense of Enforcement, Amount Forgone Recovery due to Expense of Enforcement, Amount Share-based Payment Arrangement [Abstract] Share-Based Payment Arrangement [Abstract] Entity Tax Identification Number Entity Tax Identification Number Net lease cost Lease, Cost Stock-based compensation expense related to inventories Share-Based Payment Arrangement, Amount Capitalized Statistical Measurement [Axis] Statistical Measurement [Axis] Balance Sheet Location [Domain] Balance Sheet Location [Domain] Entity Interactive Data Current Entity Interactive Data Current Debt Securities, Available-for-sale [Table] Debt Securities, Available-for-Sale [Table] Adjustments to reconcile net income to net cash provided by operating activities: Adjustments, Noncash Items, to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Product revenues, net Product revenues, net Product [Member] Entity Well-known Seasoned Issuer Entity Well-known Seasoned Issuer Laboratory equipment, other equipment and furniture Laboratory equipment, other equipment and furniture Laboratory Equipment, Other Equipment and Furniture [Member] Laboratory Equipment, Other Equipment and Furniture Other assets Other Assets [Member] Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] Operating lease assets Deferred Tax Assets, Operating Lease Assets Deferred Tax Assets, Operating Lease Assets Measure: Measure [Axis] Commitments and Contingencies Disclosure [Abstract] Commitments and Contingencies Disclosure [Abstract] Name Outstanding Recovery, Individual Name Revenue Recognition Revenue from Contract with Customer [Policy Text Block] Gross Amounts Not Offset Derivative Asset, Subject to Master Netting Arrangement, Deduction of Financial Instrument Not Offset Entity Incorporation, State or Country Code Entity Incorporation, State or Country Code Goodwill Goodwill and Intangible Assets, Goodwill, Policy [Policy Text Block] Weighted-average discount rate Weighted Average Discount Rate [Abstract] Weighted Average Discount Rate [Abstract] Schedule of Deferred Tax Assets and Liabilities Schedule of Deferred Tax Assets and Liabilities [Table Text Block] Hedging Activities Derivatives, Policy [Policy Text Block] Antidilutive Securities Excluded from Computation of Earnings Per Share Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] 2024 Finite-Lived Intangible Asset, Expected Amortization, Year One Operating cash flows from operating leases Operating Lease, Payments Common stock, shares outstanding (in shares) Beginning balance (in shares) Ending balance (in shares) Common Stock, Shares, Outstanding PEO PEO [Member] Intangible assets Deferred Tax Assets Intangibles The component of income tax expense for the period representing the increase (decrease) in the entity's deferred tax assets related to intangible assets. Concentration of Credit Risk Concentration Risk, Credit Risk, Policy [Policy Text Block] Auditor Location Auditor Location Common stock, par value (in dollars per share) Common Stock, Par or Stated Value Per Share Finance leases Finance Lease, Right-of-Use Asset, after Accumulated Amortization [Abstract] Remaining milestone payment Business Combination, Remaining Milestone Payment Business Combination, Remaining Milestone Payment Net cash used in investing activities Net Cash Provided by (Used in) Investing Activities Fair Value Equity Securities, FV-NI, Current Other long-term liabilities, foreign currency forward contracts Derivative Liability, Noncurrent Outstanding Aggregate Erroneous Compensation Amount Outstanding Aggregate Erroneous Compensation Amount Measurement Input Type [Domain] Measurement Input Type [Domain] Credit Facility [Axis] Credit Facility [Axis] $200.01–$342.73 Exercise Price Range From Dollars 200.01 to Dollars$342.73 [Member] Exercise Price Range From Dollars 200.01 to Dollars$342.73 Total liabilities Liabilities Total current taxes Current Income Tax Expense (Benefit) Expected stock price volatility Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Abstract] Debt securities fair value, unrealized loss position Debt Securities, Available-for-Sale, Unrealized Loss Position Fair Value of Contingent Consideration In-process Research and Development Assets and Contingent Payments [Policy Text Block] Disclosure of accounting policy for costs assigned to identifiable tangible and intangible assets and contingent payments of an acquired entity to be used in the research and development activities of the combined enterprise. Measurement Frequency [Domain] Measurement Frequency [Domain] Property and Equipment Property, Plant and Equipment Disclosure [Text Block] Common stock, number of votes per share Common Stock, Votes Per Each Share Common Stock, Votes Per Each Share Fair value of cash flow hedges Cash Flow Hedge Derivative Instrument Assets at Fair Value Non-Rule 10b5-1 Arrangement Adopted Non-Rule 10b5-1 Arrangement Adopted [Flag] R&D capitalization Deferred Tax Assets, in Process Research and Development Property, Plant and Equipment, Type [Domain] Long-Lived Tangible Asset [Domain] Long-Lived Tangible Asset [Domain] Number of leases Lease Agreement, Number of Leases Represents the number of leases entered by the reporting entity. Research and Development Expenses Research, Development, and Computer Software, Policy [Policy Text Block] Marketable Securities Marketable Securities, Policy [Policy Text Block] Net payments due to CRISPR Therapeutics related to finite-lived intangible assets Noncash Financing Or Investing Activities, Collaborative Arrangement, Milestone Payments Due Noncash Financing Or Investing Activities, Collaborative Arrangement, Milestone Payments Due Decrease in unrecognized tax benefits is reasonably possible Decrease in Unrecognized Tax Benefits is Reasonably Possible Options outstanding and exercisable, weighted-average exercise price (in dollars per share) Share-Based Payment Arrangement, Option, Exercise Price Range, Outstanding, Weighted Average Exercise Price Awards Close in Time to MNPI Disclosures, Table Awards Close in Time to MNPI Disclosures [Table Text Block] State Current State and Local Tax Expense (Benefit) Additional In-License Agreements and Other Arrangements Additional In-License Agreements and Other Arrangements [Member] Additional In-License Agreements and Other Arrangements Total current assets Assets, Current Beginning balance Ending balance Business Combination, Contingent Consideration, Liability Equity Securities Corporate equity securities Equity Securities [Member] Schedule of Significant Customers Schedules of Concentration of Risk, by Risk Factor [Table Text Block] Supplemental disclosure of cash flow information: Supplemental Cash Flow Information [Abstract] Derivative Liability, Current, Statement of Financial Position [Extensible Enumeration] Derivative Liability, Current, Statement of Financial Position [Extensible Enumeration] Computers and software Technology Equipment [Member] Number of purchase periods Share-based Compensation Arrangement by Share-based Payment Award, Number of Purchase Periods Share-based Compensation Arrangement by Share-based Payment Award, Number of Purchase Periods Net Income Per Common Share Earnings Per Share, Policy [Policy Text Block] Goodwill and Other Intangible Assets Goodwill and Intangible Assets Disclosure [Text Block] Repurchases of common stock (in shares) Repurchases of common stock (in shares) Stock Repurchased During Period, Shares Operating Loss and Tax Credit, Carryforwards [Table] Operating Loss and Tax Credit, Carryforwards [Table] Schedule reflecting pertinent information, such as tax authority, amounts, and expiration dates, of net operating loss carryforwards, including an assessment of the likelihood of utilization and tax credit carryforwards. Contingent liabilities Contingent Liabilities Amount of material contingent liabilities outstanding Marketable Securities and Equity Investments Cash, Cash Equivalents, and Marketable Securities [Text Block] Concentration risk percentage Concentration Risk, Percentage Current taxes: Current Income Tax Expense (Benefit), Continuing Operations [Abstract] Entrada Therapeutics Entrada Therapeutics [Member] Entrada Therapeutics Schedule of Accumulated Other Comprehensive Income (Loss) Schedule of Accumulated Other Comprehensive Income (Loss) [Table Text Block] Unrecognized tax benefits, deferred tax liabilities, gross Unrecognized Tax Benefits, Deferred Tax Liabilities, Gross Unrecognized Tax Benefits, Deferred Tax Liabilities, Gross State taxes, net of federal benefit Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Percent Granted (in dollars per share) Granted (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value 2028 Finite-Lived Intangible Asset, Expected Amortization, Year Five Issuance of common stock under benefit plans Stock Issued During Period, Value, Employee Benefit Plan Nonemployee Stock Option Nonemployee Stock Option [Member] Nonemployee Stock Option 2027 Finance Lease, Liability, to be Paid, Year Four Asset-backed securities Asset-Backed Securities [Member] Accounts Receivable Accounts Receivable [Policy Text Block] Net cash provided by operating activities Net Cash Provided by (Used in) Operating Activities Exercisable Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value Schedule of Finite-Lived Intangible Assets, Future Amortization Expense Schedule of Finite-Lived Intangible Assets, Future Amortization Expense [Table Text Block] Other current liabilities, contingent consideration Business Combination, Contingent Consideration, Liability, Current Erroneously Awarded Compensation Recovery Erroneously Awarded Compensation Recovery [Table] Accredo Health Group, Inc. Accredo Health Group, Inc. [Member] Accredo Health Group, Inc. Depreciation and amortization expenses Depreciation, Depletion and Amortization Deferred costs Deferred Costs Award Timing, How MNPI Considered Award Timing, How MNPI Considered [Text Block] Share Repurchase Program 2023 Share Repurchase Program 2023 [Member] Share Repurchase Program 2023 Indemnification claims Indemnification Claims Amount of indemnification claims currently outstanding Length of lease Lessee Leasing Arrangements, Capital Leases, Term of Contract Lessee Leasing Arrangements, Capital Leases, Term of Contract Commercial paper Commercial paper Commercial Paper [Member] Total long-lived assets Long-Lived Assets Valuation allowance Valuation allowance Deferred Tax Assets, Valuation Allowance Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table] Finance Leases Finance Lease, Liability, to be Paid, Fiscal Year Maturity [Abstract] Revenues related to performance obligations Contract with Customer, Liability, Revenue Recognized Debt covenant, increase in consolidated leverage ratio Debt Covenant, Increase In Consolidated Leverage Ratio Debt Covenant, Increase In Consolidated Leverage Ratio Prepaid expenses and other current assets Restricted Cash and Cash Equivalents Schedule of Cash Equivalents and Available-for-sale Securities [Table] Schedule of Cash, Cash Equivalents and Available-for-sale Securities [Table] Schedule of the cash and cash equivalents and available-for-sale investments held by the entity. Catalyst Biosciences Catalyst Biosciences [Member] Catalyst Biosciences On Foreign Currency Forward Contracts Accumulated Gain (Loss), Net, Cash Flow Hedge, Parent [Member] Long-term marketable securities Marketable Securities Noncurrent [Member] Marketable Securities Noncurrent Schedule of Additional Cash Flow Information Condensed Cash Flow Statement [Table Text Block] Equity securities without readily determinable fair value, amount Equity Securities without Readily Determinable Fair Value, Amount Less: amount representing interest Finance Lease And Operating Lease, Liability, Undiscounted Excess Amount Finance Lease And Operating Lease, Liability, Undiscounted Excess Amount Property, Plant and Equipment, Type [Axis] Long-Lived Tangible Asset [Axis] Long-Lived Tangible Asset [Axis] Preferred stock, shares issued (in shares) Preferred Stock, Shares Issued Entity Emerging Growth Company Entity Emerging Growth Company United Kingdom UNITED KINGDOM Other intangible assets, net Intangible assets, net (excluding goodwill), total Intangible Assets, Net (Excluding Goodwill) Gross deferred tax assets Deferred Tax Assets, Gross 2024 Lessee, Operating Lease, Liability, to be Paid, Year One Pay vs Performance Disclosure, Table Pay vs Performance [Table Text Block] Antidilutive Securities [Axis] Antidilutive Securities [Axis] Title Trading Arrangement, Individual Title Common Stock Common Stock [Member] Individual: Individual [Axis] Entity Address, Postal Zip Code Entity Address, Postal Zip Code Statute of limitations expiration Unrecognized Tax Benefits, Reduction Resulting from Lapse of Applicable Statute of Limitations Income Statement Location [Domain] Income Statement Location [Domain] Other assets, foreign currency forward contracts Derivative Asset, Noncurrent Unrecognized tax benefits, income tax penalties and interest expense Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense Minimum Minimum [Member] Shares used in per share calculations: Weighted Average Number of Shares Outstanding, Diluted [Abstract] Moderna Agreement Moderna Agreement [Member] Moderna Agreement [Member] Area of real estate property (in square feet) Area of Real Estate Property Cash Cash Statement of Cash Flows [Abstract] Statement of Cash Flows [Abstract] Assets Assets [Abstract] Award Timing MNPI Disclosure Award Timing MNPI Disclosure [Text Block] Product revenue accruals Product Sales Accrued Liabilities Total of product sales allowances and reserves that reflect a liability established to represent expected future costs. Net foreign currency transaction loss Gain (Loss), Foreign Currency Transaction, before Tax Payments in connection with common stock withheld for employee tax obligations Payment, Tax Withholding, Share-Based Payment Arrangement Other Deferred Tax Assets, Other U.S. Treasury securities U.S. Treasury securities US Treasury Securities [Member] Net cash used in financing activities Net Cash Provided by (Used in) Financing Activities Deferred tax assets Deferred Income Tax Assets, Net Lessee, Lease, Description [Line Items] Lessee, Lease, Description [Line Items] Retained Earnings Retained Earnings [Member] Summary of cash, cash equivalents and marketable securities Schedule of Cash, Cash Equivalents and Available-for-sale Securities [Line Items] -- None. No documentation exists for this element. -- Adjustment to Non-PEO NEO Compensation Footnote Adjustment to Non-PEO NEO Compensation Footnote [Text Block] Basic (in dollars per share) Basic net income per common share (in dollars per share) Earnings Per Share, Basic Accounting Policies [Abstract] Accounting Policies [Abstract] Derivative Asset, Current, Statement of Financial Position [Extensible Enumeration] Derivative Asset, Current, Statement of Financial Position [Extensible Enumeration] Class of Treasury Stock [Table] Class of Treasury Stock [Table] Corporate Headquarters Fan Pier Leases [Member] Represents the fan pier leases. Erroneous Compensation Analysis Erroneous Compensation Analysis [Text Block] Net deferred tax assets Deferred Tax Assets, Net Total intrinsic value of stock options exercised Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value Share Repurchase Program 2020 Share Repurchase Program 2020 [Member] Share Repurchase Program 2020 [Member] Operating Lease, Liability, Current, Statement of Financial Position [Extensible List] Operating Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration] Document Transition Report Document Transition Report Award Timing Predetermined Award Timing Predetermined [Flag] Accounts payable Increase (Decrease) in Accounts Payable Gross Unrealized Gains Equity Securities, FV-NI, Unrealized Gain Schedule of Unrecognized Tax Benefits Summary of Income Tax Contingencies [Table Text Block] Share Repurchase Program 2021 Share Repurchase Program 2021 [Member] Share Repurchase Program 2021 Optional renewal term length Lessee Leasing Arrangements, Capital Leases, Renewal Term Lessee Leasing Arrangements, Capital Leases, Renewal Term Entity Public Float Entity Public Float Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Property, Plant and Equipment [Abstract] Property, Plant and Equipment [Abstract] Derivative Instrument [Axis] Derivative Instrument [Axis] Gross Unrealized Gains Debt and Equity Securities, Unrealized Gain Debt and Equity Securities, Unrealized Gain All Trading Arrangements All Trading Arrangements [Member] Less: accumulated depreciation Property, Plant, and Equipment and Finance Lease Right-of-Use Asset, Accumulated Depreciation and Amortization All Adjustments to Compensation All Adjustments to Compensation [Member] 2026 Finance Lease And Operating Lease, Liability, Payment, Due Year Three Finance Lease And Operating Lease, Liability, Payment, Due Year Three Compensation Amount Outstanding Recovery Compensation Amount Marketable securities Marketable Securities [Member] Marketable Securities [Member] Arbor Biotechnologies, Inc Arbor Biotechnologies, Inc [Member] Arbor Biotechnologies, Inc Gross Amounts Presented Derivative Asset Cancelled (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value Operating lease liabilities Deferred Tax Liabilities, Leasing Arrangements Finance lease liabilities Deferred Tax Assets, Lease Obligation Deferred Tax Assets, Lease Obligation Total deferred taxes Deferred Income Tax Expense (Benefit) Total cash received from employees as a result of employee stock option exercises Proceeds from Stock Options Exercised Subsequent Event Type [Axis] Subsequent Event Type [Axis] Statement of Comprehensive Income [Abstract] Statement of Comprehensive Income [Abstract] Share-based Payment Arrangement, Option, Exercise Price Range [Table] Share-Based Payment Arrangement, Option, Exercise Price Range [Table] Total finance lease liabilities Present value of lease liabilities Finance Lease, Liability Forfeited (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Document Financial Statement Error Correction Document Financial Statement Error Correction [Flag] Cancelled (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period Market share price (in dollars per share) Share Price Share-based payment arrangements (in shares) Incremental Common Shares Attributable to Dilutive Effect of Share-Based Payment Arrangements Losses (gains) on equity securities Equity Securities, FV-NI, Unrealized Gain (Loss) Exercise price, high end of range (in dollars 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Schedule of Share-Based Payment Award, Employee Stock Purchase Plan, Valuation Assumptions [Table Text Block] Tax credit carryforwards Tax Credit Carryforward, Amount Cash and cash equivalents Cash and Cash Equivalents, at Carrying Value Payment to acquire ViaCyte, net of cash acquired Payments to Acquire Businesses, Net of Cash Acquired Common stock withheld for employee tax obligations (in shares) Share-Based Payment Arrangement, Shares Withheld for Tax Withholding Obligation Grant date fair values Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Fair Value Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Fair Value Credit Facility [Domain] Credit Facility [Domain] Time deposits Time deposits Bank Time Deposits [Member] Basis spread on variable rate (as a percent) Debt Instrument, Basis Spread on Variable Rate Property and equipment useful life Property, Plant and Equipment, Useful Life Compensation Actually Paid vs. Other Measure Compensation Actually Paid vs. Other Measure [Text Block] Fair Value Debt and Equity Securities, Fair Value Debt and Equity Securities, Fair Value Schedule of Other Long Term Liabilities Other Noncurrent Liabilities [Table Text Block] Less: amount representing interest Finance Lease, Liability, Undiscounted Excess Amount Total lease payments Finance Lease And Operating Lease, Liability, Payments, Due Finance Lease And Operating Lease, Liability, Payments, Due Additional paid-in capital Additional Paid in Capital, Common Stock Additional Paid-in Capital Additional Paid-in Capital [Member] Document Annual Report Document Annual Report Sale of equity securities Proceeds from Sale of Equity Securities, FV-NI Effect of potentially dilutive securities: Weighted Average Number of Shares Outstanding, Diluted, Adjustment [Abstract] Balance Sheet Location [Axis] Balance Sheet Location [Axis] Commitments and Contingencies Commitments Disclosure [Text 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Finance lease liabilities Other current liabilities Finance Lease, Liability, Current Schedule of Offsetting Assets Offsetting Assets [Table Text Block] Share-based compensation arrangement by share-based payment award, purchase price of common stock, percent Share-Based Compensation Arrangement by Share-Based Payment Award, Purchase Price of Common Stock, Percent State and Local Jurisdiction State and Local Jurisdiction [Member] Work-in-process Inventory, Work in Process, Net of Reserves Non-GAAP Measure Description Non-GAAP Measure Description [Text Block] Other Deferred Tax Liabilities, Other Entity Current Reporting Status Entity Current Reporting Status Concentration Risk Type [Domain] Concentration Risk Type [Domain] Income from operations Operating Income (Loss) Cash and cash equivalents Cash and Cash Equivalents [Member] Total deferred tax liabilities Deferred Tax Liabilities, Gross Revenue from External Customers by Products and Services [Table] Revenue from External Customers by Products and Services [Table] Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] Schedule of Unrecognized Stock-Based Compensation Expense Schedule of Unrecognized Share-based Compensation Expense [Table Text Block] Disclosure as of the latest balance-sheet date presented of the total compensation cost related to outstanding, nonvested share-based compensation awards not yet recognized, net of estimated forfeitures, and the weighted average period over which those unrecognized costs are expected to be reported. Cloud Computing Service Contracts Cloud Computing Service Contracts [Policy Text Block] Cloud Computing Service Contracts Property and Equipment Property, Plant and Equipment, Policy [Policy Text Block] Other comprehensive (loss) income: Other Comprehensive Income (Loss), Net of Tax [Abstract] 2006 Stock and Option Plan Stock and Option Plan 2006 [Member] The element describes the details pertaining to the 2006 Stock and Option Plan. Weighted-average Exercise Price Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures [Abstract] Forgone Recovery due to Disqualification of Tax Benefits, Amount Forgone Recovery due to Disqualification of Tax Benefits, Amount Awards Close in Time to MNPI Disclosures Awards Close in Time to MNPI Disclosures [Table] Components of income (loss) before provision for (benefit from) income taxes Income (Loss) from Continuing Operations before Equity Method Investments, Income Taxes, Noncontrolling Interest [Abstract] Septerna Inc Septerna, Inc [Member] Septerna Inc Shareholders’ equity: Equity, Including Portion Attributable to Noncontrolling Interest [Abstract] Tranche one Share-Based Payment Arrangement, Tranche One [Member] Variable Rate [Domain] Variable Rate [Domain] Pay vs Performance Disclosure [Line Items] Entity Voluntary Filers Entity Voluntary Filers Statistical Measurement [Domain] Statistical Measurement [Domain] Underlying Security Market Price Change Underlying Security Market Price Change, Percent Royalty payable Accrued Royalties, Current Debt covenant, consolidated leverage ratio Debt Covenant, Consolidated Leverage Ratio Consolidated leverage ratio that must be maintained in order to be in compliance with debt covenants. Beginning of the period (in shares) End of the period (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number Other current liabilities Other Current Liabilities [Member] Statement of Stockholders' Equity [Abstract] Statement of Stockholders' Equity [Abstract] Investments, Debt and Equity Securities [Abstract] Investments, Debt and Equity Securities [Abstract] Revolving Credit Facility Revolving Credit Facility [Member] Schedule of Cash, Cash Equivalents and Marketable Securities Cash, Cash Equivalents and Investments [Table Text Block] Effect of changes in exchange rates on cash Effect of Exchange Rate on Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Continuing Operations Collaborative arrangement development and regulatory potential milestone additional payments Collaborative Arrangement Development And Regulatory Potential Milestone Additional Payments, Maximum Collaborative 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Indefinite-Lived (Excluding Goodwill) Geographical [Axis] Geographical [Axis] Deferred Tax Assets Deferred Tax Assets [Member] Deferred Tax Assets [Member] Income Taxes Income Tax Disclosure [Text Block] Concentration Risk [Line Items] Concentration Risk [Line Items] Total property and equipment, gross Property, Plant, and Equipment and Finance Lease Right-of-Use Asset, before Accumulated Depreciation and Amortization Leases Lessee, Leases [Policy Text Block] Number of approved cystic fibrosis medicines Number of Approved Cystic Fibrosis Medicines Number of approved cystic fibrosis medicines Preferred stock, par value (in dollars per share) Preferred Stock, Par or Stated Value Per Share Fair Value, Recurring and Nonrecurring [Table] Fair Value, Recurring and Nonrecurring [Table] Total liabilities Derivative Liability, Subject to Master Netting Arrangement, before Offset PEO Total Compensation Amount PEO Total Compensation Amount Hedging Relationship [Axis] Hedging Relationship [Axis] Property, Plant and Equipment [Table] Property, Plant and Equipment [Table] Trading Arrangements, by Individual Trading Arrangements, by Individual [Table] Level 3 Fair Value, Inputs, Level 3 [Member] Outstanding at beginning of period (in shares) Outstanding at end of period (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number Buildings and improvements Building and Building Improvements [Member] Non-PEO NEO Average Compensation Actually Paid Amount Non-PEO NEO Average Compensation Actually Paid Amount Interest income Investment Income, Interest and Dividend Weighted-average grant-date fair value, granted ( in usd per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value Net income Net income Net income Net Income (Loss) Total current liabilities Liabilities, Current Derivative Contract [Domain] Derivative Contract [Domain] Schedule of Cash Flow Hedging Instruments Schedule of Notional Amounts of Outstanding Derivative Positions [Table Text Block] 2025 Finance Lease, Liability, to be Paid, Year Two Foreign Currency Translation and Transactions Foreign Currency Transactions and Translations Policy [Policy Text Block] Changed Peer Group, Footnote Changed Peer Group, Footnote [Text Block] Schedule of Components of Lease in Balance Sheets Assets And Liabilities, Lessee [Table Text Block] Assets And Liabilities, Lessee [Table Text Block] Other revenues Collaborative and Royalty [Member] Collaborative and Royalty [Member] Company Selected Measure Name Company Selected Measure Name Leases Lessee, Operating Leases [Text Block] Property and equipment, net Total property and equipment, net Property, Plant, and Equipment and Finance Lease Right-of-Use Asset, after Accumulated Depreciation and Amortization Liabilities and Shareholders’ Equity Liabilities and Equity [Abstract] Repurchases of common stock Repurchases of common stock Stock Repurchased During Period, Value Schedule of Shares Issued Under Employee Stock Purchase Plan Schedule of Share-Based Compensation, Employee Stock Purchase Plan, Activity [Table Text Block] Derivative Instruments, Gain (Loss) [Table] Derivative Instruments, Gain (Loss) [Table] Concentration Risk Benchmark [Domain] Concentration Risk Benchmark [Domain] Amounts reclassified from accumulated other comprehensive income (loss) Reclassification from AOCI, Current Period, Net of Tax, Attributable to Parent Unrealized loss Gross Unrealized Losses Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax Exercised (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period United States Income (Loss) from Continuing Operations before Income Taxes, Domestic Cost of sales Cost of Goods and Services Sold Vesting period Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period Exercise Price Range [Domain] Exercise Price Range [Domain] Schedule of Indefinite-Lived Intangible Assets Schedule of Indefinite-Lived Intangible Assets [Table Text Block] Comprehensive Income Comprehensive Income, Policy [Policy Text Block] Name Measure Name Name Forgone Recovery, Individual Name Goodwill Goodwill Increases related to prior period tax positions Unrecognized Tax Benefits, Increase Resulting from Prior Period Tax Positions Lessee, Lease, Description [Table] Lessee, Lease, Description [Table] Asset Acquisition [Domain] Asset Acquisition [Domain] Underlying Securities Award Underlying Securities Amount Other Other Countries Outside of the United States and the United Kingdom [Member] Other Countries Outside of the United States and the United Kingdom [Member] Accumulated Other Comprehensive Income (Loss) Comprehensive Income (Loss) Note [Text Block] Accounts receivable, net Increase (Decrease) in Accounts Receivable McKesson Corporation McKesson Corporation [Member] McKesson Corporation [Member] Selling, general and administrative expenses Selling, General and Administrative Expenses [Member] Long-term operating lease liabilities Operating Lease, Liability, Noncurrent Revenue from External Customer [Line Items] Revenue from External Customer [Line Items] Purchase of common stock Payment To Acquire Common Stock Payment To Acquire Common Stock Schedule of Foreign Exchange Contracts Schedule of Foreign Exchange Contracts, Statement of Financial Position [Table Text Block] Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward] Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward] Reclassification out of Accumulated Other Comprehensive Income [Axis] Reclassification out of Accumulated Other Comprehensive Income [Axis] Income Statement Location [Axis] Income Statement Location [Axis] Jeffrey Leiden Center for Cell and Genetic Therapies Jeffrey Leiden Center for Cell and Genetic Therapies [Member] Jeffrey Leiden Center for Cell and Genetic Therapies License agreement, contingency payment License Agreement, Contingency Payment License Agreement, Contingency Payment Issuance of common stock under benefit plans (in shares) Stock Issued During Period, Shares, Employee Benefit Plan Total stock-based compensation expense, net of tax Share-Based Payment Arrangement, Expense, after Tax Schedule of Operating Lease, Liability, Maturity Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block] Foreign currency forward contracts Foreign Exchange Forward [Member] Common Stock, Preferred Stock and Equity Plans Common Stock, Preferred Stock and Equity Plans Disclosure [Text Block] Disclosures related to shares available for future issuance, descriptions of the stock and option plans, and the rights associated with each share. Europe Europe [Member] Cash and Cash Equivalents Cash and Cash Equivalents, Policy [Policy Text Block] Product and Service [Domain] Product and Service [Domain] Other Performance Measure, Amount Other Performance Measure, Amount Right-of-use assets obtained in exchange for lease obligations Right-Of-Use Asset Obtained In Exchange For Lease Liability [Abstract] Right-Of-Use Asset Obtained In Exchange For Lease Liability [Abstract] Schedule of Lease Cost Lease, Cost [Table Text Block] Inventories Increase (Decrease) in Inventories Unrealized holding gains (losses) on marketable securities, net of tax of $(2.7), zero and zero, respectively Other Comprehensive Income (Loss), Available-for-Sale Securities Adjustment, Net of Tax, Portion Attributable to Parent Cash flows from investing activities: Net Cash Provided by (Used in) Investing Activities [Abstract] Derivative Instruments and Hedging Activities Disclosure [Abstract] Derivative Instruments and Hedging Activities Disclosure [Abstract] Unrealized (losses) gains on foreign currency forward contracts, tax Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), after Reclassification, Tax, Parent Plan Name [Domain] Plan Name [Domain] Additional Balance Sheet Detail Additional Financial Information Disclosure [Text Block] Number of shares authorized (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Authorized Outstanding (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term Trading Arrangement: Trading Arrangement [Axis] Contingent consideration, measurement input (percent) Business Combination, Contingent Consideration, Liability, Measurement Input Publicly Traded Companies Sale Publicly Traded Companies Sale [Member] Publicly Traded Companies Sale [Member] Schedule of PSU Activity Share-Based Payment Arrangement, Performance Shares, Outstanding Activity [Table Text Block] Use of Estimates Use of Estimates, Policy [Policy Text Block] Lloyds Pharmacy Lloyds Pharmacy [Member] Lloyds Pharmacy Corporate equity securities Equity Securities, FV-NI and without Readily Determinable Fair Value [Abstract] Total marketable debt securities Debt Securities, Available-for-Sale [Abstract] Entity File Number Entity File Number Audit Information [Abstract] Audit Information [Abstract] Thereafter Lessee, Operating Lease, Liability, to be Paid, after Year Five Discount Rate Measurement Input, Discount Rate [Member] Derivative term Derivative, Term of Contract On Available-For-Sale Debt Securities AOCI, Accumulated Gain (Loss), Debt Securities, Available-for-Sale, Parent [Member] Allowance for credit loss for available-for-sale debt securities Debt Securities, Available-for-Sale, Allowance for Credit Loss Decreases related to prior period tax positions Unrecognized Tax Benefits, Decrease Resulting from Prior Period Tax Positions Auditor Firm ID Auditor Firm ID Amortization of intangible assets Amortization of Intangible Assets Entity Shell Company Entity Shell Company Research, development and commercial contract costs Accrued Research Development and Commercial Contract Costs This element represents the carrying value as of the balance sheet date of obligations incurred through that date and payable for R&D and commercial of the entity. It is used to reflect the current portion of liabilities (due within one year or within the normal operating cycle, if longer). Restatement Determination Date Restatement Determination Date KALYDECO KALYDECO [Member] KALYDECO inventories, net Increases related to current period tax positions Unrecognized Tax Benefits, Increase Resulting from Current Period Tax Positions Other liabilities Increase (Decrease) in Other Operating Liabilities Rule 10b5-1 Arrangement Adopted Rule 10b5-1 Arrangement Adopted [Flag] Cash, cash equivalents and restricted cash—beginning of period Cash, cash equivalents and restricted cash—end of period Cash, cash equivalents and restricted cash per consolidated statements of cash flows Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents Potential awards, percent of target shares, minimum Share-Based Compensation By Share-Based Payment Award, Award Percentage Of Target, Minimum Share-Based Compensation By Share-Based Payment Award, Award Percentage Of Target, Minimum Duration of purchase period Share-based Compensation Arrangement by Share-based Payment Award, Duration of Purchase Period Share-based Compensation Arrangement by Share-based Payment Award, Duration of Purchase Period Variable lease cost Variable Lease, Cost ORKAMBI ORKAMBI [Member] ORKAMBI [Member] Operating lease cost Operating Lease, Cost Unrealized loss position for greater than twelve months Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, 12 Months or Longer Common stock, shares issued (in shares) Common Stock, Shares, Issued Vested (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period Schedule of Company's Net Unrealized (Losses) Gains on Corporate Equity Securities Unrealized Gain (Loss) on Investments [Table Text Block] Total financial assets Assets, Fair Value Disclosure Foreign Currency Translation Adjustment Foreign Currency Forward Contract Accumulated Foreign Currency Adjustment Attributable to Parent [Member] CRISPR T1D CRISPR T1D [Member] CRISPR T1D Weighted-average Recognition Period Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition Comprehensive income Comprehensive Income (Loss), Net of Tax, Attributable to Parent Collaborative arrangement, reimbursement of contingency payment, percent Collaborative Arrangement, Reimbursement Of Contingency Payment, Percent Collaborative Arrangement, Reimbursement Of Contingency Payment, Percent Tax-related prepaid and receivables Tax Related Prepaid and Receivables Tax Related Prepaid and Receivables Domestic Tax Authority Domestic Tax Authority [Member] Entity Address, Address Line One Entity Address, Address Line One Up-front payment Collaborative Arrangement, Up-front License Fee The amount of the up-front license fee paid by the entity pursuant to a collaborative arrangement. 2025 Finance Lease And Operating Lease, Liability, Payment, Due Year Two Finance Lease And Operating Lease, Liability, Payment, Due Year Two 2024 Finance Lease, Liability, to be Paid, Year One Tax related accruals Taxes Payable, Current Subsequent Event Subsequent Event [Member] Unrecognized tax benefits, income tax penalties and interest accrued Unrecognized Tax Benefits, Income Tax Penalties and Interest Accrued Operating loss carryforwards Operating Loss Carryforwards 2013 Stock and Option Plan Stock and Option Plan 2013 [Member] Stock and Option Plan 2013 [Member] Schedule of Finite-Lived Intangible Assets, Net Schedule of Finite-Lived Intangible Assets [Table Text Block] Other current liabilities Total Other Liabilities, Current Income Statement [Abstract] Income Statement [Abstract] CRSIPR A&R JDCA CRISPR A&R JDCA [Member] CRISPR Amended and restated the Original CTX001 JDCA Insider Trading Policies and Procedures Adopted Insider Trading Policies and Procedures Adopted [Flag] Cash equivalents: Cash and Cash Equivalents, Fair Value Disclosure Gross Amounts Presented Derivative Liability Option to extend lease term Lessee, Finance Lease, Term of Contract Other Other Assets, Current Amortized Cost Debt and Equity Securities, Cost Debt and Equity Securities, Cost Collaborative Arrangements by Agreement [Axis] Collaborative Arrangements by Agreement [Axis] Significant terms of collaboration arrangements, by individual agreement. Inventories Total Inventory, Net Land Land [Member] Financial Instrument [Axis] Financial Instrument [Axis] Total Shareholder Return Amount Total Shareholder Return Amount Repurchases of common stock Payments for Repurchase of Common Stock Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding Adjustment To PEO Compensation, Footnote Adjustment To PEO Compensation, Footnote [Text Block] Foreign Deferred Foreign Income Tax Expense (Benefit) Inventory Disclosure [Abstract] Inventory Disclosure [Abstract] Fair Value Hierarchy and NAV [Axis] Fair Value Hierarchy and NAV [Axis] Retained earnings Retained Earnings (Accumulated Deficit) San Diego Lease San Diego Lease [Member] San Diego Lease [Member] Share-based Compensation, Shares Authorized under Stock Option Plans, by Exercise Price Range [Axis] Exercise Price Range [Axis] Current assets: Assets, Current [Abstract] Leases [Abstract] Leases [Abstract] Deferred tax assets: Components of Deferred Tax Assets [Abstract] Entity Address, State or Province Entity Address, State or Province Compensation Actually Paid vs. Total Shareholder Return Compensation Actually Paid vs. Total Shareholder Return [Text Block] Schedule of Revenues from External Customers and Long-Lived Assets [Table] Schedule of Revenues from External Customers and Long-Lived Assets [Table] Total lease payments Finance Lease, Liability, to be Paid Cash flows from operating activities: Net Cash Provided by (Used in) Operating Activities [Abstract] Accumulated Other Comprehensive Income (Loss) [Line Items] Accumulated Other Comprehensive Income (Loss) [Line Items] Total assets Gross Amounts Recognized Derivative Asset, Subject to Master Netting Arrangement, before Offset Maximum percentage of annual compensation contributed by the participant (percent) Defined Contribution Plan, Maximum Annual Contributions Per Employee, Percent Foreign currency translation adjustment Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Adjustment, Net of Tax, Portion Attributable to Parent Other Effective Income Tax Rate Reconciliation, Other Adjustments, Percent Schedule of Stock and Stock Equity Plans Schedule of Stock and Stock Option, Equity Plans [Table Text Block] This schedule discloses the information pertaining to stock and stock option plans relating to the entity's equity. Customer [Domain] Customer [Domain] Schedule of Inventories by Type Schedule of Inventory, Current [Table Text Block] Schedule of Foreign Exchange Contracts, Condensed Consolidated Statements of Operations Reclassification out of Accumulated Other Comprehensive Income [Table Text Block] 2024 Finance Lease And Operating Lease, Liability, Payment, Due Next Twelve Months Finance Lease And Operating Lease, Liability, Payment, Due Next Twelve Months Revenues from External Customers and Long-Lived Assets [Line Items] Revenues from External Customers and Long-Lived Assets [Line Items] Stock Options Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward] Name of Property [Domain] Name of Property [Domain] Effective tax rate Effective tax rate Effective Income Tax Rate Reconciliation, Percent Total operating lease liabilities Present value of lease liabilities Operating Lease, Liability Collaborative arrangement, milestone payment Collaborative Arrangement, Milestone Payment Collaborative Arrangement, Milestone Payment Asset Acquisition [Axis] Asset Acquisition [Axis] Total Shareholder Return Vs Peer Group Total Shareholder Return Vs Peer Group [Text Block] Vesting [Domain] Vesting [Domain] Prepaid expenses and other assets Increase (Decrease) in Prepaid Expense and Other Assets Accumulated Other Comprehensive Income (Loss) Total AOCI Attributable to Parent [Member] Aggregate Erroneous Compensation Amount Aggregate Erroneous Compensation Amount Mammoth Biosciences, Inc Mammoth Biosciences, Inc [Member] Mammoth Biosciences, Inc Defined contribution plan, cost Defined Contribution Plan, Cost All Executive Categories All Executive Categories [Member] Expected annual dividends Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Payments Accumulated Other Comprehensive Income (Loss) [Table] Accumulated Other Comprehensive Income (Loss) [Table] Plan Name [Axis] Plan Name [Axis] Income tax effect Share-Based Payment Arrangement, Expense, Tax Benefit Net income per common share: Earnings Per Share [Abstract] Common stock, $0.01 par value; 500,000,000 shares authorized, 257,695,221 and 257,011,628 shares issued and outstanding, respectively Common Stock, Value, Issued Matures after one year through five years Debt Securities, Available-for-Sale, Fair Value, Maturity, Allocated and Single Maturity Date, after Year One Through Five Organization, Consolidation and Presentation of Financial Statements [Abstract] Organization, Consolidation and Presentation of Financial Statements [Abstract] Deferred income taxes Increase (Decrease) in Other Deferred Liability Awards outstanding (in shares) Share-Based Compensation Arrangement By Share-based Payment Award, Equity Instruments Outstanding, Number Share-Based Compensation Arrangement By Share-based Payment Award, Equity Instruments Outstanding, Number 2028 Finance Lease And Operating Lease, Liability, Payments, Due Year Five Finance Lease And Operating Lease, Liability, Payments, Due Year Five Deferred taxes: Deferred Income Tax Expense (Benefit), Continuing Operations [Abstract] Fair Value Cash Equivalents And Debt Securities, Available for Sale, Fair Value Disclosure Cash Equivalents And Debt Securities, Available for Sale, Fair Value Disclosure Payments on finance leases Financing cash flows from finance leases Finance Lease, Principal Payments Schedule of Finance Lease, Liability, Maturity Finance Lease, Liability, to be Paid, Maturity [Table Text Block] Revenues: Revenue from Contract with Customer [Abstract] All Individuals All Individuals [Member] Cash paid for amounts included in the measurement of lease liabilities Cash Flow, Operating Activities, Lessee [Abstract] Finance Lease, Right-of-Use Asset, Statement of Financial Position [Extensible List] Finance Lease, Right-of-Use Asset, Statement of Financial Position [Extensible Enumeration] Other (expense) income, net Other Nonoperating Income (Expense) Entity Filer Category Entity Filer Category Non-PEO NEO Average Total Compensation Amount Non-PEO NEO Average Total Compensation Amount Statement [Table] Statement [Table] Other long-term liabilities, contingent consideration Contingent consideration Business Combination, Contingent Consideration, Liability, Noncurrent Current Fiscal Year End Date Current Fiscal Year End Date Schedule of Weighted-Average Remaining Lease Terms and Discount Rates Schedule of Weighted-Average Remaining Lease Terms and Discount Rates Related to Leases [Table Text Block] Schedule of Weighted-Average Remaining Lease Terms and Discount Rates Related to Leases [Table Text Block] Number of shares authorized to be repurchased Stock Repurchase Program, Authorized Amount Derivative Instruments and Hedging Activities Disclosures [Line Items] Derivative Instruments and Hedging Activities Disclosures [Line Items] Unrecognized tax benefits Balance at beginning of the period Balance at end of period Unrecognized Tax Benefits Income Tax Authority [Axis] Income Tax Authority [Axis] PEO Name PEO Name Other Other Sundry Liabilities, Current Weighted-average Remaining Contractual Life Weighted Average, Remaining Contractual Life [Abstract] -- None. No documentation exists for this element. -- Preferred stock, shares authorized (in shares) Preferred Stock, Shares Authorized Base Rate Base Rate [Member] Buildings and improvements Building [Member] Preferred stock, shares outstanding (in shares) Preferred Stock, Shares Outstanding Tax credit carryforwards Deferred Tax Assets, Tax Credit Carryforwards Schedule of Prepaid, and Other Assets Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Table Text Block] Stock-based compensation Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-Based Compensation Cost Schedule of Supplemental Cash Flow Information Lease, Supplemental Cash Flow Information [Table Text Block] Lease, Supplemental Cash Flow Information [Table Text Block] Unrecognized tax benefits, increase (decrease) in deferred tax assets, gross Unrecognized Tax Benefits, Increase (Decrease) In Deferred Tax Assets, Gross Unrecognized Tax Benefits, Increase (Decrease) In Deferred Tax Assets, Gross Other Other Accrued Liabilities, Current Product Concentration Risk Product Concentration Risk [Member] Euro Euro Member Countries, Euro Statement of Financial Position [Abstract] Statement of Financial Position [Abstract] $77.31–$100.00 Exercise Price Range from Dollars 77.31 to Dollars 100.00 [Member] Exercise Price Range from Dollars 77.31 to Dollars 100.00 Total shareholders’ equity Beginning balance Ending balance Equity, Attributable to Parent Net unrecognized tax benefits which would affect the tax rate if recognized Unrecognized Tax Benefits that Would Impact Effective Tax Rate U.S. tax on foreign earnings, net of credits Effective Income Tax Rate Reconciliation, Repatriation of Foreign Earnings, Percent Restricted stock units (including PSUs) Restricted stock units (including PSUs) Restricted Stock [Member] Concentration Risk Type [Axis] Concentration Risk Type [Axis] Expected term (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term Income before provision for income taxes Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest Payments related to finite-lived intangible assets Payments to Acquire Intangible Assets Not designated as hedging instrument Not Designated as Hedging Instrument [Member] Hedging Designation [Domain] Hedging Designation [Domain] Level 2 Fair Value, Inputs, Level 2 [Member] Proceeds from finance leases and other financing activities Proceeds From Finance Leases And Other Financing Activities Proceeds From Finance Leases And Other Financing Activities $150.01–$200.00 Exercise Price Range from Dollars 150.01 to Dollars 200.00 [Member] Represents the range of exercise prices from $150.01 to $200.00 per share for the purpose of disclosing shares potentially issuable under outstanding stock options, as well as other option information. Weighted-average remaining lease term (in years) Weighted-Average Remaining Lease [Abstract] Weighted-Average Remaining Lease [Abstract] Investment in equity securities and notes receivable Payments to Acquire Equity Securities, FV-NI $100.01–$150.00 Exercise Price Range from Dollars 100.01 to Dollars 150.00 [Member] Represents the range of exercise prices from $100.01 to $150.00 per share for the purpose of disclosing shares potentially issuable under outstanding stock options, as well as other option information. Foreign currency translation adjustment Unrecognized Tax Benefits, Increase Resulting from Foreign Currency Translation Increase (Decrease) in Stockholders' Equity Increase (Decrease) in Stockholders' Equity [Roll Forward] Named Executive Officers, Footnote Named Executive Officers, Footnote [Text Block] Increase in unrecognized tax benefits Unrecognized Tax Benefits, Period Increase (Decrease) Document Fiscal Period Focus Document Fiscal Period Focus Estimated Useful lives Finite-Lived Intangible Asset, Useful Life Accrued expenses Increase (Decrease) in Accrued Liabilities and Other Operating Liabilities 2027 Lessee, Operating Lease, Liability, to be Paid, Year Four Outstanding at beginning of period (in dollars per share) Outstanding at end of period (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price Stock-based compensation expense Share-Based Payment Arrangement, Noncash Expense Foreign Tax Authority Foreign Tax Authority [Member] City Area Code City Area Code Editas Medicine, Inc. Editas Medicine, Inc. [Member] Editas Medicine, Inc. Earnings Per Share Earnings Per Share [Text Block] Product and Service [Axis] Product and Service [Axis] Document Fiscal Year Focus Document Fiscal Year Focus Geographical [Domain] Geographical [Domain] Weighted-average 
Grant-date Fair Value Weighted-average 
Grant-date Fair Value Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Additional Disclosures [Abstract] Lease agreement initial term Lessee, Operating Lease, Term of Contract Stock-based Compensation Expense Compensation Related Costs, Policy [Policy Text Block] Share Repurchase Program [Domain] Share Repurchase Program [Domain] Nature of Business and Accounting Policies Organization, Consolidation, Basis of Presentation, Business Description and Accounting Policies [Text Block] Exercise price, low end of range (in dollars per share) Share-Based Payment Arrangement, Option, Exercise Price Range, Lower Range Limit Schedule of Outstanding and Exercisable Options Share-Based Payment Arrangement, Option, Activity [Table Text Block] Exercise Price Award Exercise Price CRISPR CRISPR [Member] CRISPR Equity, Class of Treasury Stock [Line Items] Equity, Class of Treasury Stock [Line Items] Goodwill and Intangible Assets Disclosure [Abstract] Goodwill and Intangible Assets Disclosure [Abstract] Cash paid for income taxes Income Taxes Paid, Net Present value of lease liabilities Finance Lease And Operating Lease, Liability Finance Lease And Operating Lease, Liability Schedule of Stock-based Compensation Expense by Line Item Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block] Total liabilities and shareholders’ equity Liabilities and Equity Amortized Cost Debt Securities, Available-for-Sale, Amortized Cost Other assets Other Assets, Noncurrent Peer Group Total Shareholder Return Amount Peer Group Total Shareholder Return Amount Risk-free interest rate Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate Operating lease assets Total operating lease assets Operating Lease, Right-of-Use Asset Equity Valuation Assumption Difference, Footnote Equity Valuation Assumption Difference, Footnote [Text Block] Foreign Current Foreign Tax Expense (Benefit) Indefinite-Lived Intangible Assets [Line Items] Indefinite-Lived Intangible Assets [Line Items] Currency [Axis] Currency [Axis] Finance Lease, Liability, Current, Statement of Financial Position [Extensible List] Finance Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration] Arrangement Duration Trading Arrangement Duration In-process research and development In Process Research and Development [Member] Entity Address, City or Town Entity Address, City or Town Award Timing MNPI Considered Award Timing MNPI Considered [Flag] Marketable securities and other assets Marketable Securities And Other Noncurrent Assets [Member] Marketable Securities And Other Noncurrent Assets Upfront and milestone payments Collaborative Arrangement, Milestone And Upfront Payment Collaborative Arrangement, Milestone And Upfront Payment Schedule of Fair Value of Our Contingent Consideration Liabilities Schedule of Business Acquisitions by Acquisition, Contingent Consideration [Table Text Block] Tax-related liabilities Tax Related Liabilities, Noncurrent Tax Related Liabilities, Noncurrent SOFR Secured Overnight Financing Rate (SOFR) [Member] Secured Overnight Financing Rate (SOFR) Lease agreements number of buildings Lease Agreement, Number of Buildings Represents number of buildings under lease agreements. Number of shares remaining for repurchases Stock Repurchase Program, Remaining Authorized Repurchase Amount Derivative Instruments and Hedging Activities Disclosures [Table] Derivative Instruments and Hedging Activities Disclosures [Table] Termination Date Trading Arrangement Termination Date Proceeds received Proceeds from Sale and Maturity of Marketable Securities Common stock, shares authorized (in shares) Common Stock, Shares Authorized Cloud computing service contracts, amortization Capitalized Computer Software, Amortization Fair Value Debt securities Total Debt Securities, Available-for-Sale Gross Unrealized Gains Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax Tax Carryforwards [Line Items] Tax Carryforwards [Line Items] -- None. No documentation exists for this element. -- CRISPR Therapeutics CRISPR Therapeutics AG [Member] CRISPR Therapeutics AG Indefinite-lived Intangible Assets [Axis] Indefinite-Lived Intangible Assets [Axis] Allocation of net profits and net losses, percent Collaborative Arrangement, Allocation Of Net Profits And Losses, Percent Collaborative Arrangement, Allocation Of Net Profits And Losses, Percent Measurement Input Type [Axis] Measurement Input Type [Axis] Derivative [Line Items] Derivative [Line Items] Award Timing Disclosures [Line Items] Restricted stock vested in period, total fair value Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Fair Value Matures after five years Debt Securities, Available-for-Sale, Fair Value, Maturity, Allocated and Single Maturity Date, after Year 5 Through 10 TRIKAFTA/KAFTRIO TRIKAFTA/KAFTRIO [Member] TRIKAFTA/KAFTRIO Australian dollar Australia, Dollars Tranche three Share-Based Payment Arrangement, Tranche Three [Member] Income Taxes Income Tax, Policy [Policy Text Block] Prepaid expenses and other current assets Prepaid expenses and other current assets Prepaid Expense and Other Assets, Current 2026 Finite-Lived Intangible Asset, Expected Amortization, Year Three Other Other Countries Outside of the United States and Europe [Member] Other Countries Outside of the United States and Europe [Member] Insider Trading Arrangements [Line Items] AOCI Attributable to Parent, Net of Tax [Roll Forward] AOCI Attributable to Parent, Net of Tax [Roll Forward] Outstanding Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value Number of installments Share-based Compensation Arrangement By Share-based Payment Award, Number Of Installments Share-based Compensation Arrangement By Share-based Payment Award, Number Of Installments Other current liabilities Other Liabilities, Current [Abstract] Entity Registrant Name Entity Registrant Name Material Terms of Trading Arrangement Material Terms of Trading Arrangement [Text Block] Award Timing Method Award Timing Method [Text Block] Foreign income tax rate differential Effective Income Tax Rate Reconciliation, Foreign Income Tax Rate Differential, Percent 2025 Finite-Lived Intangible Asset, Expected Amortization, Year Two Acquired In-process Research and Development Expenses In Process Research and Development, Policy [Policy Text Block] Adjustment to Compensation, Amount Adjustment to Compensation Amount Tranche two Share-Based Payment Arrangement, Tranche Two [Member] Cost of sales Cost of Sales [Member] Change in fair value of contingent consideration Decrease in fair value of contingent consideration Decrease in fair value of contingent payments Business Combination, Contingent Consideration Arrangements, Change in Amount of Contingent Consideration, Liability Deferred tax liabilities: Components of Deferred Tax Liabilities [Abstract] Auditor Name Auditor Name Compensation Actually Paid vs. Net Income Compensation Actually Paid vs. Net Income [Text Block] Peer Group Issuers, Footnote Peer Group Issuers, Footnote [Text Block] Schedule of Financial Assets Subject to Fair Value Measurements Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block] Exercisable (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price Entity Central Index Key Entity Central Index Key Thereafter Finance Lease And Operating Lease, Liability, Payments, Due After Year Five Finance Lease And Operating Lease, Liability, Payments, Due After Year Five Stock-based compensation expense Share-Based Payment Arrangement, Expense Non-Rule 10b5-1 Arrangement Terminated Non-Rule 10b5-1 Arrangement Terminated [Flag] Finite-lived intangible assets, gross Finite-Lived Intangible Assets, Gross Finished goods Inventory, Finished Goods, Net of Reserves Income Tax Authority [Domain] Income Tax Authority [Domain] Payroll and benefits Employee-related Liabilities, Current Percent of Total Gross Product Revenues Revenue Benchmark [Member] Name Trading Arrangement, Individual Name Total other comprehensive (loss) income Other comprehensive income (loss), net of tax Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent Revenue Product revenues, net Total product revenues, net Revenue from Contract with Customer, Excluding Assessed Tax Entity [Domain] Entity [Domain] Amendment Flag Amendment Flag Legal Entity [Axis] Legal Entity [Axis] Gross Amounts Offset Derivative Liability, Subject to Master Netting Arrangement, Asset Offset Operating leases Operating Lease, Weighted Average Discount Rate, Percent Cash paid for interest Interest Paid, Excluding Capitalized Interest, Operating Activities Interest expense Interest Income (Expense), Net Number of shares (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Shares Issued in Period Matures within one year Debt Securities, Available-for-Sale, Fair Value, Maturity, Allocated and Single Maturity Date, Year One Financial instruments carried at fair value (asset positions): Assets, Fair Value Disclosure [Abstract] Finance leases Finance Lease, Weighted Average Remaining Lease Term Leasehold improvements Leasehold Improvements [Member] Diluted (in shares) Diluted weighted-average common shares outstanding (in shares) Weighted Average Number of Shares Outstanding, Diluted Forgone Recovery, Explanation of Impracticability Forgone Recovery, Explanation of Impracticability [Text Block] Debt securities, available-for-sale, realized gain (loss) Debt Securities, Available-for-Sale, Realized Gain (Loss) Cloud computing service contracts Capitalized Computer Software, Gross Total assets Offsetting Derivative Assets [Abstract] Purchases of property and equipment Payments to Acquire Property, Plant, and Equipment Company Selected Measure Amount Company Selected Measure Amount Legal Offset Derivative Asset, Fair Value, Offset Against Collateral, Net of Not Subject to Master Netting Arrangement, Policy Election Restricted investments, at fair value Restricted Investments, at Fair Value Options outstanding and exercisable, weighted-average remaining contractual life Share-Based Payment Arrangement, Option, Exercise Price Range, Outstanding, Weighted Average Remaining Contractual Term Average price paid per share (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Per Share Weighted Average Price of Shares Purchased Stock options outstanding and exercisable Share-Based Payment Arrangement, Option, Exercise Price Range [Line Items] Performance period Share-Based Compensation by Share-Based Payment Award, Performance Period Share-Based Compensation by Share-Based Payment Award, Performance Period Finance lease cost Lease, Cost [Abstract] Total assets Assets Name Awards Close in Time to MNPI Disclosures, Individual Name Share Repurchase Program [Axis] Share Repurchase Program [Axis] Thereafter Finance Lease, Liability, to be Paid, after Year Five Gross Unrealized Losses Debt and Equity Securities, Unrealized Loss Debt and Equity Securities, Unrealized Loss Stock-based compensation expense APIC, Share-Based Payment Arrangement, Increase for Cost Recognition Operating cash flows from finance leases Finance Lease, Interest Payment on Liability Vested (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value Non-NEOs Non-NEOs [Member] Total product revenues outside of the United States Total long-lived assets outside of the United States Outside the United States [Member] Outside the United States [Member] Cash flows from financing activities: Net Cash Provided by (Used in) Financing Activities [Abstract] Non-PEO NEO Non-PEO NEO [Member] Marketable securities: Marketable Securities Adjustment to Compensation: Adjustment to Compensation [Axis] Original cost Amortized Cost Equity Securities, FV-NI, Cost Gross Amounts Offset Derivative Asset, Subject to Master Netting Arrangement, Liability Offset Basic (in shares) Basic weighted-average common shares outstanding (in shares) Weighted Average Number of Shares Outstanding, Basic Collaborative arrangement, right to exclusively license, number of targets Collaborative Arrangement, Right To License, Number Of Targets Collaborative Arrangement, Right To License, Number Of Targets Property and equipment Deferred Tax Liabilities, Property, Plant and Equipment Concentration Risk Benchmark [Axis] Concentration Risk Benchmark [Axis] Schedule of Reconciliation of the Provision for (Benefit From) Income Taxes Income Tax Expense (Benefit) Continuing Operations, Income Tax Reconciliation [Table Text Block] This block of text may be used to disclose all or parts of the required information for reconciliation of income tax provisions. Schedule of Indefinite-Lived Intangible Assets by Major Class [Table] Schedule of Indefinite-Lived Intangible Assets [Table] Estimated Amortization Expense Finite-Lived Intangible Assets, Net, Amortization Expense, Fiscal Year Maturity [Abstract] Issuances of common stock under benefit plans Proceeds, Issuance of Shares, Share-Based Payment Arrangement, Including Option Exercised Pay vs Performance Disclosure Pay vs Performance Disclosure [Table] Statement [Line Items] Statement [Line Items] Statement [Line Items] Concentration Risk [Table] Concentration Risk [Table] Total stock-based compensation expense included in “Total costs and expenses” Share-Based Payment Arrangement, Expensed and Capitalized, Amount Acquired intangibles Deferred Tax Liabilities, Intangible Assets Name of Property [Axis] Name of Property [Axis] Reclassification out of Accumulated Other Comprehensive Income [Domain] Reclassification out of Accumulated Other Comprehensive Income [Domain] Offering period (in months) Share-based Compensation Arrangement by Share-based Payment Award, Offering Period Share-based Compensation Arrangement by Share-based Payment Award, Offering Period Aggregate Intrinsic Value Aggregate intrinsic value [Abstract] -- None. No documentation exists for this element. --