Business Acquisition [Axis] Business Acquisition [Axis] Foreign Current Foreign Tax Expense (Benefit) Foreign Currency Translation and Transactions Foreign Currency Transactions and Translations Policy [Policy Text Block] British pound sterling United Kingdom, Pounds Deferred tax assets Deferred Income Tax Assets, Net Total finance lease assets Finance Lease, Right-of-Use Asset, after Accumulated Amortization Property, Plant and Equipment [Abstract] Property, Plant and Equipment [Abstract] Deferred taxes: Deferred Income Tax Expense (Benefit), Continuing Operations [Abstract] Preferred stock, shares outstanding (in shares) Preferred Stock, Shares Outstanding Unrealized holding gains (losses) on marketable securities, net Other Comprehensive Income (Loss), Available-for-Sale Securities Adjustment, Net of Tax, Portion Attributable to Parent Property and equipment, net Finance Lease, Right-Of-Use Asset, Gross Finance Lease, Right-Of-Use Asset, Gross Present value of lease liabilities Present value of lease liabilities Finance Lease, Liability Net other liabilities Business Combination, Recognized Identifiable Assets Acquired, Goodwill, and Liabilities Assumed, Net Other Liabilities Business Combination, Recognized Identifiable Assets Acquired, Goodwill, and Liabilities Assumed, Net Other Liabilities Financial Instruments [Domain] Financial Instruments [Domain] Restrictions on Cash and Cash Equivalents [Table] Restrictions on Cash and Cash Equivalents [Table] Basis spread on variable rate (as a percent) Debt Instrument, Basis Spread on Variable Rate 2026 Finance Lease, Liability, to be Paid, Year Four Depreciation expense Depreciation Exercised (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period Schedule of Indefinite-Lived Intangible Assets by Major Class [Table] Schedule of Indefinite-Lived Intangible Assets [Table] Net deferred tax assets Deferred Tax Assets, Net Operating leases Operating Lease, Weighted Average Discount Rate, Percent Revenues and Property and Equipment by Location Schedule of Revenue from External Customers and Long-Lived Assets, by Geographical Areas [Table Text Block] Stock-based Compensation Expense Compensation Related Costs, Policy [Policy Text Block] Additional paid-in capital Additional Paid in Capital, Common Stock Reclassification out of Accumulated Other Comprehensive Income [Axis] Reclassification out of Accumulated Other Comprehensive Income [Axis] Other non-cash items, net Other Noncash Income (Expense) State Current State and Local Tax Expense (Benefit) 2025 Finance Lease, Liability, to be Paid, Year Three Lessee, Lease, Description [Table] Lessee, Lease, Description [Table] Measurement Input Type [Domain] Measurement Input Type [Domain] Antidilutive Securities Excluded from Computation of Earnings Per Share Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Antidilutive securities excluded from computation of earnings per share (in shares) Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Operating Leases Lessee, Operating Lease, Liability, to be Paid [Abstract] Share Repurchase Program [Domain] Share Repurchase Program [Domain] Other Effective Income Tax Rate Reconciliation, Other Adjustments, Percent Thereafter Lessee, Operating Lease, Liability, to be Paid, after Year Five Collaborative Arrangements by Agreement [Domain] Collaborative Arrangements by Agreement [Domain] Collaborative Arrangements by Agreement [Domain] Potential awards, percent of target shares, maximum Share-Based Compensation By Share-Based Payment Award, Award Percentage Of Target, Maximum Share-Based Compensation By Share-Based Payment Award, Award Percentage Of Target, Maximum Schedule of Stock Options Outstanding and Exercisable Share-Based Payment Arrangement, Option, Exercise Price Range [Table Text Block] Equity Component [Domain] Equity Component [Domain] Subsequent Event Type [Domain] Subsequent Event Type [Domain] Discount Rate Measurement Input, Discount Rate [Member] Options outstanding (in shares) Share-Based Payment Arrangement, Option, Exercise Price Range, Shares Outstanding Increases related to current period tax positions Unrecognized Tax Benefits, Increase Resulting from Current Period Tax Positions Options outstanding, weighted-average exercise price (in dollars per share) Share-Based Payment Arrangement, Option, Exercise Price Range, Outstanding, Weighted Average Exercise Price Summary of Unrecognized Tax Benefits Summary of Income Tax Contingencies [Table Text Block] Amortization of leased assets Finance Lease, Right-of-Use Asset, Amortization Lessee, Lease, Description [Line Items] Lessee, Lease, Description [Line Items] Fair Value Debt Securities Total Debt Securities, Available-for-Sale Hedging Designation [Domain] Hedging Designation [Domain] Operating Lease, Liability, Current, Statement of Financial Position [Extensible List] Operating Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration] Supplemental disclosure of cash flow information: Supplemental Cash Flow Information [Abstract] Forfeited (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Plan Name [Domain] Plan Name [Domain] Entity Address, State or Province Entity Address, State or Province ESPP share issuances Employee Stock [Member] Other comprehensive (loss) income: Other Comprehensive Income (Loss), Net of Tax [Abstract] Outstanding (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term 2026 Finance Lease And Operating Lease, Liability, Payments, Due Year Four Finance Lease And Operating Lease, Liability, Payments, Due Year Four Acquired In-process Research and Development Expenses In Process Research and Development, Policy [Policy Text Block] Award Type [Axis] Award Type [Axis] Operating lease liabilities Other current liabilities Operating Lease, Liability, Current Expired (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Expirations in Period Finance lease cost Lease, Cost [Abstract] All Currencies [Domain] All Currencies [Domain] Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table] Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table] Collaborative arrangement, option payment Collaborative Arrangement, Option Payment Collaborative Arrangement, Option Payment Costs and expenses: Costs and Expenses [Abstract] Total liabilities Liabilities Time deposits Time deposits Bank Time Deposits [Member] Operating leases Operating Lease, Weighted Average Remaining Lease Term Verve Verve [Member] Verve Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] Schedule of Foreign Exchange Contracts, Condensed Consolidated Statements of Operations Reclassification out of Accumulated Other Comprehensive Income [Table Text Block] Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding Fair Value, Measurements, Fair Value Hierarchy [Domain] Fair Value Hierarchy and NAV [Domain] Schedule of Collaborative Arrangement Costs Collaborative Arrangement and Arrangement Other than Collaborative [Table Text Block] Revolving Credit Facility Revolving Credit Facility [Member] ApolLo1 Bio, LLC ApolLo1 Bio, LLC [Member] ApolLo1 Bio, LLC Revenue Recognition Revenue from Contract with Customer [Policy Text Block] Current taxes: Current Income Tax Expense (Benefit), Continuing Operations [Abstract] On Available-For-Sale Debt Securities AOCI, Accumulated Gain (Loss), Debt Securities, Available-for-Sale, Parent [Member] Document Type Document Type SOFR Loan Secured Overnight Financing Rate (SOFR) Overnight Index Swap Rate [Member] Debt securities, available-for-sale, realized gain (loss) Debt Securities, Available-for-Sale, Realized Gain (Loss) Property and equipment useful life Property, Plant and Equipment, Useful Life Revenue from External Customer [Line Items] Revenue from External Customer [Line Items] Financial instruments carried at fair value (asset positions): Assets, Fair Value Disclosure [Abstract] Finite-Lived Intangible Assets, Major Class Name [Domain] Finite-Lived Intangible Assets, Major Class Name [Domain] Beginning of the period (in dollars per share) End of the period (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value Finance Leases Finance Lease, Liability, to be Paid [Abstract] Asset Acquisition [Axis] Asset Acquisition [Axis] Walgreen Co. Walgreen Co. [Member] Walgreen Co. [Member] Total deferred taxes Deferred Income Tax Expense (Benefit) Share-based Compensation, Shares Authorized under Stock Option Plans, by Exercise Price Range [Axis] Exercise Price Range [Axis] Non-financial performance shares Non-Financial Performance Shares [Member] Non-Financial Performance Shares Schedule of Offsetting Liabilities Offsetting Liabilities [Table Text Block] SYMDEKO/SYMKEVI SYMDEKO/SYMKEVI [Member] SYMDEKO/SYMKEVI [Member] Tranche one Share-Based Payment Arrangement, Tranche One [Member] Debt Securities, Available-for-sale [Table] Debt Securities, Available-for-Sale [Table] Derivative Instruments, Gain (Loss) [Table] Derivative Instruments, Gain (Loss) [Table] Accounts Receivable Accounts Receivable [Policy Text Block] Income Statement Location [Axis] Income Statement Location [Axis] Tranche three Share-Based Payment Arrangement, Tranche Three [Member] Accrued expenses Total Accrued Liabilities, Current Stock-based compensation expense: Share-based Compensation Allocation [Abstract] -- None. No documentation exists for this element. -- Net cash used in financing activities Net Cash Provided by (Used in) Financing Activities Amortized Cost Cash Equivalents And Debt Securities, Available for Sale Cash Equivalents And Debt Securities, Available for Sale Accounting Policies [Abstract] Accounting Policies [Abstract] Variable lease cost Variable Lease, Cost Prepaid expenses and other current assets Prepaid expenses and other current assets Prepaid Expense and Other Assets, Current Foreign income tax rate differential Effective Income Tax Rate Reconciliation, Foreign Income Tax Rate Differential, Percent Customer [Axis] Customer [Axis] Other current liabilities Other Liabilities, Current [Abstract] Other long-term liabilities Other Noncurrent Liabilities [Member] Schedule of Assumptions Used to Estimate the Grant Date Fair Value of Options Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Long-term finance lease liabilities Finance Lease, Liability, Noncurrent Schedule of Components of Provision for (Benefit From) Income Taxes Schedule of Components of Income Tax Expense (Benefit) [Table Text Block] Gross Unrealized Gains Equity Securities, FV-NI, Unrealized Gain Weighted-average Recognition Period Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition Exercisable (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term Derivative Contract [Domain] Derivative Contract [Domain] Entity Registrant Name Entity Registrant Name Average price paid per share (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Per Share Weighted Average Price of Shares Purchased Exercise price, high end of range (in dollars per share) Share-Based Payment Arrangement, Option, Exercise Price Range, Upper Range Limit Uncertain tax positions Effective Income Tax Rate Reconciliation, Uncertain Tax Positions, Percent Effective Income Tax Rate Reconciliation, Uncertain Tax Positions, Percent Collaborative arrangement development and regulatory potential milestone payments maximum Collaborative Arrangement Development And Regulatory Potential Milestone Payments Maximum Represents the potential milestone amount to be paid by the entity under the collaboration agreement if drug candidates are approved and commercialized. Leases [Abstract] Leases [Abstract] Net operating loss Deferred Tax Assets, Operating Loss Carryforwards Minimum Minimum [Member] Entity Emerging Growth Company Entity Emerging Growth Company Common stock, par value (in dollars per share) Common Stock, Par or Stated Value Per Share Percentage of employees eligible for acceleration of equity awards (less than) (percent) Percentage of employees eligible for acceleration of equity awards Percentage of employees eligible for acceleration of equity awards Number of optional renewal terms Lessee, Operating Lease, Number Of Renewal Options Lessee, Operating Lease, Number Of Renewal Options Commitments and Contingencies Disclosure [Abstract] Commitments and Contingencies Disclosure [Abstract] Sale of equity securities Proceeds from Sale of Debt and Equity Securities, FV-NI, Held-for-investment Fair Value Measurements Fair Value Disclosures [Text Block] Trading Symbol Trading Symbol Entity File Number Entity File Number Financial performance shares Financial Performance Shares [Member] Financial Performance Shares Accumulated Other Comprehensive Income (Loss) [Line Items] Accumulated Other Comprehensive Income (Loss) [Line Items] Options outstanding, weighted-average remaining contractual life Share-Based Payment Arrangement, Option, Exercise Price Range, Outstanding, Weighted Average Remaining Contractual Term Foreign Deferred Foreign Income Tax Expense (Benefit) Investment in equity securities and notes receivable Payment to Acquire Preferred Stock and Notes Receivable Payment to Acquire Preferred Stock and Notes Receivable Hedging Activities Derivatives, Policy [Policy Text Block] Granted (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period Effective tax rate Effective tax rate Effective Income Tax Rate Reconciliation, Percent Concentration Risk Benchmark [Axis] Concentration Risk Benchmark [Axis] Use of Estimates Use of Estimates, Policy [Policy Text Block] Business Combination Business Combination Disclosure [Text Block] Accounts payable Increase (Decrease) in Accounts Payable Total purchase price Business Combination, Recognized Identifiable Assets Acquired, Goodwill, and Liabilities Assumed, Net Concentration risk percentage Concentration Risk, Percentage Income Taxes Income Tax Disclosure [Text Block] Finished goods Inventory, Finished Goods, Net of Reserves Credit Facility [Domain] Credit Facility [Domain] Basic (in dollars per share) Basic net income per common share (in dollars per share) Earnings Per Share, Basic Revenues from External Customers and Long-Lived Assets [Line Items] Revenues from External Customers and Long-Lived Assets [Line Items] Restricted stock vested in period, total fair value Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Fair Value Indefinite-lived Intangible Assets [Axis] Indefinite-Lived Intangible Assets [Axis] Prepaid expenses Prepaid Expense, Current Allowance for credit loss for available-for-sale debt securities Debt Securities, Available-for-Sale, Allowance for Credit Loss Derivative Instruments, Gain (Loss) [Line Items] Derivative Instruments, Gain (Loss) [Line Items] Entity Interactive Data Current Entity Interactive Data Current Laboratory equipment, other equipment and furniture Laboratory equipment, other equipment and furniture Laboratory Equipment, Other Equipment and Furniture [Member] Laboratory Equipment, Other Equipment and Furniture Long-term intercompany receivable write-off Effective Income Tax Rate Reconciliation, Intercompany Receivable Write-Off, Percent Effective Income Tax Rate Reconciliation, Intercompany Receivable Write-Off, Percent Prepaid expenses and other current assets Prepaid Expenses and Other Current Assets [Member] Property, Plant and Equipment [Table] Property, Plant and Equipment [Table] Changes in operating assets and liabilities: Increase (Decrease) in Operating Capital [Abstract] Operating lease assets Deferred Tax Assets, Operating Lease Assets Deferred Tax Assets, Operating Lease Assets Money market funds Money market funds Money Market Funds [Member] 2027 Finance Lease, Liability, to be Paid, Year Five Schedule of Stock-based Compensation Expense by Line Item Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block] Total other comprehensive (loss) income Other comprehensive income (loss), net of tax Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent Other comprehensive (loss) income before reclassifications OCI, before Reclassifications, Net of Tax, Attributable to Parent Repurchases of common stock Payments for Repurchase of Common Stock Weighted-average discount rate Weighted Average Discount Rate [Abstract] Weighted Average Discount Rate [Abstract] Income Taxes Income Tax, Policy [Policy Text Block] Marketable Securities Marketable Securities, Policy [Policy Text Block] Optional term of lease agreement (in years) Lessee, Operating Lease, Renewal Term Commercial paper Commercial Paper, Not Included with Cash and Cash Equivalents [Member] Current assets: Assets, Current [Abstract] Unrecognized tax benefits, income tax penalties and interest expense Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense Asset Acquisition [Domain] Asset Acquisition [Domain] Additional Balance Sheet Detail Additional Financial Information Disclosure [Text Block] Intangible assets Deferred Tax Assets Intangibles The component of income tax expense for the period representing the increase (decrease) in the entity's deferred tax assets related to intangible assets. Retained earnings Retained Earnings (Accumulated Deficit) $200.01–$286.27 Exercise Price Range From Dollars 200.01 to Dollars $286.27 [Member] Exercise Price Range From Dollars 200.01 to Dollars $286.27 Recurring basis Fair Value, Recurring [Member] Exercisable (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price Components of income (loss) before provision for (benefit from) income taxes Income (Loss) from Continuing Operations before Equity Method Investments, Income Taxes, Noncontrolling Interest [Abstract] Remaining milestone payment Business Combination, Remaining Milestone Payment Business Combination, Remaining Milestone Payment Total collaborative arrangement costs included in costs and expenses Costs And Expenses [Member] Costs And Expenses Document Fiscal Year Focus Document Fiscal Year Focus Payments on finance leases Financing cash flows from finance leases Finance Lease, Principal Payments R&D capitalization Deferred Tax Assets, in Process Research and Development Indefinite-Lived Intangible Assets [Line Items] Indefinite-Lived Intangible Assets [Line Items] Other current liabilities, contingent consideration Business Combination, Contingent Consideration, Liability, Current Fair Value Hierarchy and NAV [Axis] Fair Value Hierarchy and NAV [Axis] Canadian dollar Canada, Dollars Total current taxes Current Income Tax Expense (Benefit) Product revenues, net Product revenues, net Product [Member] Skyhawk Therapeutics Inc Skyhawk Therapeutics Inc [Member] Skyhawk Therapeutics Inc Fair Value of In-process Research and Development Assets and Contingent Payments In-process Research and Development Assets and Contingent Payments [Policy Text Block] Disclosure of accounting policy for costs assigned to identifiable tangible and intangible assets and contingent payments of an acquired entity to be used in the research and development activities of the combined enterprise. Common stock, number of votes per share Common Stock, Votes Per Each Share Common Stock, Votes Per Each Share Inventories Increase (Decrease) in Inventories Other Other Sundry Liabilities, Noncurrent Stock-based compensation Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-Based Compensation Cost Equity securities without readily determinable fair value, amount Equity Securities without Readily Determinable Fair Value, Amount Number of leases Lease Agreement, Number of Leases Represents the number of leases entered by the reporting entity. Common stock, shares outstanding (in shares) Beginning balance (in shares) Ending balance (in shares) Common Stock, Shares, Outstanding Goodwill Goodwill Goodwill Other current liabilities Other Current Liabilities [Member] Property, Plant and Equipment, Type [Axis] Long-Lived Tangible Asset [Axis] Long-Lived Tangible Asset [Axis] Derivative Asset, Noncurrent, Statement of Financial Position [Extensible Enumeration] Derivative Asset, Noncurrent, Statement of Financial Position [Extensible Enumeration] Additional In-License Agreements and Other Arrangements [Member] Additional In-License Agreements and Other Arrangements [Member] Additional In-License Agreements and Other Arrangements Provision for income taxes Provision for income taxes Income Tax Expense (Benefit) Geographical [Domain] Geographical [Domain] Valuation allowance Valuation allowance Deferred Tax Assets, Valuation Allowance Hedging Relationship [Axis] Hedging Relationship [Axis] Entity Public Float Entity Public Float Expected annual dividends Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Payments Balance Sheet Location [Domain] Balance Sheet Location [Domain] Cost of sales Cost of Goods and Services Sold Gross Amounts Presented Derivative Liability Number of purchase periods Share-based Compensation Arrangement by Share-based Payment Award, Number of Purchase Periods Share-based Compensation Arrangement by Share-based Payment Award, Number of Purchase Periods Total liabilities Derivative Liability, Subject to Master Netting Arrangement, before Offset Operating Loss and Tax Credit, Carryforwards [Table] Operating Loss and Tax Credit, Carryforwards [Table] Schedule reflecting pertinent information, such as tax authority, amounts, and expiration dates, of net operating loss carryforwards, including an assessment of the likelihood of utilization and tax credit carryforwards. Contingent liabilities Contingent Liabilities Amount of material contingent liabilities outstanding Collaborative Arrangement and Arrangement Other than Collaborative [Domain] Collaborative Arrangement and Arrangement Other than Collaborative [Domain] Percent of Accounts Receivable Accounts Receivable [Member] Entrada Therapeutics Entrada Therapeutics [Member] Entrada Therapeutics Unrecognized tax benefits, deferred tax liabilities, gross Unrecognized Tax Benefits, Deferred Tax Liabilities, Gross Unrecognized Tax Benefits, Deferred Tax Liabilities, Gross Common stock, $0.01 par value; 500,000,000 shares authorized, 257,011,628 and 254,479,046 shares issued and outstanding, respectively Common Stock, Value, Issued Business Acquisition, Acquiree [Domain] Business Acquisition, Acquiree [Domain] Schedule of Potential Gross Common Equivalent Shares Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Accredo Health Group, Inc. Accredo Health Group, Inc. [Member] Accredo Health Group, Inc. Cash, cash equivalents and restricted cash—beginning of period Cash, cash equivalents and restricted cash—end of period Cash, cash equivalents and restricted cash per consolidated statements of cash flows Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents Foreign Income (Loss) from Continuing Operations before Income Taxes, Foreign In-process Research and Development Assets Goodwill and Intangible Assets Indefinite-Lived Assets [Policy Text Block] Describes an entity's accounting policy for indefinite-lived intangible assets (that is, those intangible assets not subject to amortization). This accounting policy also may address how the entity assesses whether events and circumstances continue to support an indefinite useful life and how the entity assesses and measures impairment of such assets. Current liabilities: Liabilities, Current [Abstract] Total cash received from employees as a result of employee stock option exercises Proceeds from Stock Options Exercised Share Repurchase Program 2023 Share Repurchase Program 2023 [Member] Share Repurchase Program 2023 Indemnification claims Indemnification Claims Amount of indemnification claims currently outstanding Length of lease Lessee Leasing Arrangements, Capital Leases, Term of Contract Lessee Leasing Arrangements, Capital Leases, Term of Contract Interest on lease liabilities Finance Lease, Interest Expense Schedule of Company's Net Unrealized (Losses) Gains on Corporate Equity Securities Unrealized Gain (Loss) on Investments [Table Text Block] Reclassification out of Accumulated Other Comprehensive Income Reclassification out of Accumulated Other Comprehensive Income [Member] Income Statement Location [Domain] Income Statement Location [Domain] Debt covenant, increase in consolidated leverage ratio Debt Covenant, Increase In Consolidated Leverage Ratio Debt Covenant, Increase In Consolidated Leverage Ratio Schedule of Cash Equivalents and Available-for-sale Securities [Table] Schedule of Cash, Cash Equivalents and Available-for-sale Securities [Table] Schedule of the cash and cash equivalents and available-for-sale investments held by the entity. Amendment Flag Amendment Flag Catalyst Biosciences Catalyst Biosciences [Member] Catalyst Biosciences Operating lease cost Operating Lease, Cost Legal Offset Derivative Asset, Fair Value, Offset Against Collateral, Net of Not Subject to Master Netting Arrangement, Policy Election Less: amount representing interest Finance Lease And Operating Lease, Liability, Undiscounted Excess Amount Finance Lease And Operating Lease, Liability, Undiscounted Excess Amount ViaCyte ViaCyte [Member] ViaCyte Gross Unrealized Gains Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax Deferred tax assets: Components of Deferred Tax Assets [Abstract] Goodwill and Intangible Assets Disclosure [Abstract] Goodwill and Intangible Assets Disclosure [Abstract] Other assets Other Assets, Noncurrent Unrealized (losses) gains on foreign currency forward contracts, net of tax Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), after Reclassification, Tax, Parent Weighted-average Exercise Price Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures [Abstract] Exercisable (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number Depreciation expense Depreciation, Depletion and Amortization Lease agreement initial term Lessee, Operating Lease, Term of Contract Counterparty Name [Axis] Counterparty Name [Axis] Accumulated Other Comprehensive Income (Loss) [Table] Accumulated Other Comprehensive Income (Loss) [Table] Computers and software Technology Equipment [Member] Entity Incorporation, State or Country Code Entity Incorporation, State or Country Code Cash equivalents: Cash and Cash Equivalents [Abstract] Operating cash flows from operating leases Operating Lease, Payments Currency [Axis] Currency [Axis] Stock options Stock options Stock options Share-Based Payment Arrangement, Option [Member] Expected stock price volatility (percent) Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate Common stock, shares authorized (in shares) Common Stock, Shares Authorized Moderna Agreement Moderna Agreement [Member] Moderna Agreement [Member] Statement of Comprehensive Income [Abstract] Statement of Comprehensive Income [Abstract] Maximum Maximum [Member] Product revenue accruals Product Sales Accrued Liabilities Total of product sales allowances and reserves that reflect a liability established to represent expected future costs. Schedule of Business Acquisitions, by Acquisition [Table] Schedule of Business Acquisitions, by Acquisition [Table] Cash and cash equivalents Cash and Cash Equivalents, at Carrying Value Designated as hedging instruments Designated as Hedging Instrument [Member] Foreign derived intangible income deduction Effective Income Tax Rate Reconciliation, FDII, Percent Unrecognized tax benefits, reduction in deferred tax assets, gross Unrecognized Tax Benefits, Decrease In Deferred Tax Assets, Gross Unrecognized Tax Benefits, Decrease In Deferred Tax Assets, Gross Business Acquisition [Line Items] Business Acquisition [Line Items] Unrealized (losses) gains on foreign currency forward contracts, net of tax of $1.0, $(21.8) and $14.3, respectively Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), after Reclassification and Tax, Parent Measurement Frequency [Domain] Measurement Frequency [Domain] Summary of cash, cash equivalents and marketable securities Schedule of Cash, Cash Equivalents and Available-for-sale Securities [Line Items] -- None. No documentation exists for this element. -- Derivative Asset, Current, Statement of Financial Position [Extensible Enumeration] Derivative Asset, Current, Statement of Financial Position [Extensible Enumeration] Line of Credit Facility [Table] Line of Credit Facility [Table] Purchases of available-for-sale debt securities Payments to Acquire Debt Securities, Available-for-Sale Intangible asset Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Indefinite-Lived Intangible Assets Computers and software Computer Software, Intangible Asset [Member] Issuance of common stock under benefit plans (in shares) Stock Issued During Period, Shares, Employee Benefit Plan Corporate Headquarters Fan Pier Leases [Member] Represents the fan pier leases. Income tax effect Share-Based Payment Arrangement, Expense, Tax Benefit Sublease income Sublease Income Variable Interest Entities Consolidation, Variable Interest Entity, Policy [Policy Text Block] Accounts receivable, net Increase (Decrease) in Accounts Receivable Title of 12(b) Security Title of 12(b) Security Share Repurchase Program 2020 Share Repurchase Program 2020 [Member] Share Repurchase Program 2020 [Member] Class of Treasury Stock [Table] Class of Treasury Stock [Table] Other assets, foreign currency forward contracts Derivative Asset, Noncurrent Segment Information Segment Reporting Disclosure [Text Block] Selling, general and administrative expenses Selling, General and Administrative Expenses [Member] Liabilities and Shareholders’ Equity Liabilities and Equity [Abstract] Foreign currency translation adjustment Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Adjustment, Net of Tax, Portion Attributable to Parent U.S. Treasury securities U.S. Treasury securities US Treasury Securities [Member] Fair Value, Recurring and Nonrecurring [Table] Fair Value, Recurring and Nonrecurring [Table] Marketable Securities and Equity Investments Cash, Cash Equivalents, and Marketable Securities [Text Block] Share Repurchase Program 2021 Share Repurchase Program 2021 [Member] Share Repurchase Program 2021 Optional renewal term length Lessee Leasing Arrangements, Capital Leases, Renewal Term Lessee Leasing Arrangements, Capital Leases, Renewal Term Shares used in per share calculations: Weighted Average Number of Shares Outstanding, Diluted [Abstract] Inventories Total Inventory, Net Accounts payable Accounts Payable, Current Income Tax Authority [Axis] Income Tax Authority [Axis] Gross Unrealized Gains Debt and Equity Securities, Unrealized Gain Debt and Equity Securities, Unrealized Gain Weighted-average cost basis Amortized Cost Equity Securities, FV-NI, Cost Less: accumulated depreciation Property, Plant, and Equipment and Finance Lease Right-of-Use Asset, Accumulated Depreciation and Amortization Finance leases Finance Lease, Right-of-Use Asset, after Accumulated Amortization [Abstract] 2025 Finance Lease And Operating Lease, Liability, Payment, Due Year Three Finance Lease And Operating Lease, Liability, Payment, Due Year Three Basic (in shares) Basic weighted-average common shares outstanding (in shares) Weighted Average Number of Shares Outstanding, Basic Marketable securities Marketable Securities [Member] Marketable Securities [Member] Accrued expenses Accrued Liabilities, Current [Abstract] Schedule of Foreign Exchange Contracts Schedule of Foreign Exchange Contracts, Statement of Financial Position [Table Text Block] Arbor Biotechnologies, Inc Arbor Biotechnologies, Inc [Member] Arbor Biotechnologies, Inc Legal Offset Derivative Liability, Fair Value, Offset Against Collateral, Net of Not Subject to Master Netting Arrangement, Policy Election Finance lease liabilities Deferred Tax Assets, Lease Obligation Deferred Tax Assets, Lease Obligation Notional amount of foreign currency forward contract Derivative, Notional Amount Preferred stock, $0.01 par value; 1,000,000 shares authorized; none issued and outstanding Preferred Stock, Value, Issued Deferred costs Deferred Costs Restricted stock units (including PSUs) Restricted Stock [Member] Property, Plant and Equipment [Line Items] Property, Plant and Equipment [Line Items] Gross Amounts Not Offset Derivative Asset, Subject to Master Netting Arrangement, Deduction of Financial Instrument Not Offset Entity Well-known Seasoned Issuer Entity Well-known Seasoned Issuer Leases Lessee, Leases [Policy Text Block] Level 3 Fair Value, Inputs, Level 3 [Member] Options exercisable (in shares) Share-Based Payment Arrangement, Option, Exercise Price Range, Shares Exercisable Stock-based Compensation Expense Share-Based Payment Arrangement [Text Block] Work-in-process Inventory, Work in Process, Net of Reserves Revenue from External Customers by Products and Services [Table] Revenue from External Customers by Products and Services [Table] Interest expense Interest Income (Expense), Net Contract liabilities Other Contract Liabilities Current Other Contract liabilities, Current Schedule of Deferred Tax Assets and Liabilities Schedule of Deferred Tax Assets and Liabilities [Table Text Block] Collaborative Arrangement and Arrangement Other than Collaborative [Axis] Collaborative Arrangement and Arrangement Other than Collaborative [Axis] Land Land [Member] Share-based payment arrangements (in shares) Incremental Common Shares Attributable to Dilutive Effect of Share-Based Payment Arrangements Organization, Consolidation and Presentation of Financial Statements [Abstract] Organization, Consolidation and Presentation of Financial Statements [Abstract] AOCI Attributable to Parent, Net of Tax [Roll Forward] AOCI Attributable to Parent, Net of Tax [Roll Forward] Payment to acquire ViaCyte, net of cash acquired Payments to Acquire Businesses, Net of Cash Acquired Level 2 Fair Value, Inputs, Level 2 [Member] Goodwill expected to be tax deductible Business Acquisition, Goodwill, Expected Tax Deductible Amount Current Fiscal Year End Date Current Fiscal Year End Date Percent of awards in tranche Share-Based Compensation By Share-Based Payment Award, Percent of Awards in Tranche Share-Based Compensation By Share-Based Payment Award, Percent of Awards in Tranche Marketable securities Marketable Securities, Current Intangible assets Intangible Assets, Net (Excluding Goodwill) Tranche two Share-Based Payment Arrangement, Tranche Two [Member] Stock-based compensation expense APIC, Share-Based Payment Arrangement, Increase for Cost Recognition Schedule of Revenues from External Customers and Long-Lived Assets [Table] Schedule of Revenues from External Customers and Long-Lived Assets [Table] Concentration Risk Type [Axis] Concentration Risk Type [Axis] Total current liabilities Liabilities, Current Other Other Sundry Liabilities, Current Operating loss carryforwards, subject to expiration Deferred Tax Assets, Operating Loss Carryforwards, Subject to Expiration Net unrecognized tax benefits which would affect the tax rate if recognized Unrecognized Tax Benefits that Would Impact Effective Tax Rate Expiration period Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period Losses (gains) on equity securities Equity Securities, FV-NI, Unrealized Gain (Loss) Total assets Offsetting Derivative Assets [Abstract] Discrete tax benefit associated with an increase in U.K.'s corporate tax rate Effective Income Tax Rate Reconciliation, Change in Enacted Tax Rate, Amount Exercise price, low end of range (in dollars per share) Share-Based Payment Arrangement, Option, Exercise Price Range, Lower Range Limit Income Tax Authority [Domain] Income Tax Authority [Domain] Other financing activities Proceeds from (Payments for) Other Financing Activities Share-based Payment Arrangement, Option, Exercise Price Range [Table] Share-Based Payment Arrangement, Option, Exercise Price Range [Table] Net unrealized (losses) gains Unrealized Gain (Loss) on Investments Intangible asset impairment charges Impairment of Intangible Assets, Indefinite-Lived (Excluding Goodwill) Europe Europe [Member] Finance leases Finance Lease, Weighted Average Remaining Lease Term Fair Value Disclosures [Abstract] Fair Value Disclosures [Abstract] Fair Value Debt and Equity Securities, Fair Value Debt and Equity Securities, Fair Value Derivative Instruments and Hedging Activities Disclosure [Abstract] Derivative Instruments and Hedging Activities Disclosure [Abstract] Credit Facility [Axis] Credit Facility [Axis] Sales and maturities of available-for-sale debt securities Proceeds from Sale and Maturity of Debt Securities, Available-for-Sale Equity [Abstract] Equity [Abstract] Vested (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period Total lease payments Finance Lease And Operating Lease, Liability, Payments, Due Finance Lease And Operating Lease, Liability, Payments, Due Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Abstract] Entity Tax Identification Number Entity Tax Identification Number Number of shares authorized (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Authorized Total Finance Leas and Operating Lease, Liabilities, Payments, Due [Abstract] Finance Leas and Operating Lease, Liabilities, Payments, Due [Abstract] Common stock withheld for employee tax obligations (in shares) Share-Based Payment Arrangement, Shares Withheld for Tax Withholding Obligation Employee stock purchase program (in shares) Incremental Common Shares Attributable to Dilutive Effect of Equity Unit Purchase Agreements Research and development expenses Research and Development Expense (Excluding Acquired in Process Cost) Net increase in cash, cash equivalents and restricted cash Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect Issuance of common stock under benefit plans Stock Issued During Period, Value, Employee Benefit Plan Contingent consideration, measurement input (percent) Business Combination, Contingent Consideration, Liability, Measurement Input Entity Central Index Key Entity Central Index Key Antidilutive Securities, Name [Domain] Antidilutive Securities, Name [Domain] Corporate equity securities Equity Securities, FV-NI and without Readily Determinable Fair Value [Abstract] Finite-Lived Intangible Assets by Major Class [Axis] Finite-Lived Intangible Assets by Major Class [Axis] Common stock withheld for employee tax obligations Share-Based Payment Arrangement, Decrease for Tax Withholding Obligation Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table] Acquired In-Process Research and Development and Other Arrangements Collaborative Arrangement Disclosure [Text Block] Purchase price Business Combination, Consideration Transferred Line of credit facility, additional borrowing capacity Line Of Credit Facility Additional Borrowing Capacity Amount of increased borrowing capacity available in the future. Concentration of Credit Risk Concentration Risk, Credit Risk, Policy [Policy Text Block] Measurement Input Type [Axis] Measurement Input Type [Axis] Entity [Domain] Entity [Domain] City Area Code City Area Code Assets Assets [Abstract] Commitments and Contingencies Commitments Disclosure [Text Block] Schedule of Prepaid, and Other Assets Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Table Text Block] Total financial liabilities Financial Liabilities Fair Value Disclosure Net Income Per Common Share Earnings Per Share, Policy [Policy Text Block] Stock-based compensation expense Share-Based Payment Arrangement, Noncash Expense Operating leases Leases, Operating [Abstract] Weighted-average grant-date fair value, granted ( in usd per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value Variable Rate [Axis] Variable Rate [Axis] Other long-term liabilities Total Other Liabilities, Noncurrent Schedule of Unrecognized Stock-Based Compensation Expense Schedule of Unrecognized Share-based Compensation Expense [Table Text Block] Disclosure as of the latest balance-sheet date presented of the total compensation cost related to outstanding, nonvested share-based compensation awards not yet recognized, net of estimated forfeitures, and the weighted average period over which those unrecognized costs are expected to be reported. Other liabilities Increase (Decrease) in Other Operating Liabilities Cloud Computing Service Contracts Cloud Computing Service Contracts [Policy Text Block] Cloud Computing Service Contracts Purchases of property and equipment Payments to Acquire Property, Plant, and Equipment Derivative term Derivative, Term of Contract Weighted Average Weighted Average [Member] 2006 Stock and Option Plan Stock and Option Plan 2006 [Member] The element describes the details pertaining to the 2006 Stock and Option Plan. Thereafter Finance Lease, Liability, to be Paid, after Year Five Schedule of Earnings Per Share, Basic and Diluted Schedule of Earnings Per Share, Basic and Diluted [Table Text Block] Operating leases Right-of-Use Asset Obtained in Exchange for Operating Lease Liability Schedule of Offsetting Assets Offsetting Assets [Table Text Block] Customer [Domain] Customer [Domain] Intra-entity transfer of intellectual property rights Effective Income Tax Rate Reconciliation, Intra-Entity Transfer Of Intellectual Property Rights, Percent Effective Income Tax Rate Reconciliation, Intra-Entity Transfer Of Intellectual Property Rights, Percent Matures within one year Debt Securities, Available-for-Sale, Fair Value, Maturity, Allocated and Single Maturity Date, Year One Increase (Decrease) in Stockholders' Equity Increase (Decrease) in Stockholders' Equity [Roll Forward] Total lease payments Lessee, Operating Lease, Liability, to be Paid Entity Address, Postal Zip Code Entity Address, Postal Zip Code Debt covenant, consolidated leverage ratio Debt Covenant, Consolidated Leverage Ratio Consolidated leverage ratio that must be maintained in order to be in compliance with debt covenants. Area of real estate property (in square feet) Area of Real Estate Property Reconciliation of Unrecognized Tax Benefits, Excluding Amounts Pertaining to Examined Tax Returns [Roll Forward] Reconciliation of Unrecognized Tax Benefits, Excluding Amounts Pertaining to Examined Tax Returns [Roll Forward] Collaborative arrangement development and regulatory potential milestone additional payments Collaborative Arrangement Development And Regulatory Potential Milestone Additional Payments, Maximum Collaborative Arrangement Development And Regulatory Potential Milestone Additional Payments, Maximum Line of credit facility, maximum borrowing capacity Line of Credit Facility, Maximum Borrowing Capacity Income Tax Disclosure [Abstract] Income Tax Disclosure [Abstract] Property and equipment Deferred Tax Liabilities, Property, Plant and Equipment Summary of Cash, Cash Equivalents and Marketable Securities Cash, Cash Equivalents and Investments [Table Text Block] Cash flows from investing activities: Net Cash Provided by (Used in) Investing Activities, Continuing Operations [Abstract] Statistical Measurement [Domain] Statistical Measurement [Domain] Indefinite-lived Intangible Assets, Major Class Name [Domain] Indefinite-Lived Intangible Assets, Major Class Name [Domain] Deferred Tax Assets Deferred Tax Assets [Member] Deferred Tax Assets [Member] Proceeds received Proceeds from Sale and Maturity of Marketable Securities Schedule of Fair Value of Our Contingent Consideration Liabilities Schedule of Business Acquisitions by Acquisition, Contingent Consideration [Table Text Block] Share-based Payment Arrangement [Abstract] Share-Based Payment Arrangement [Abstract] Statute of limitations expiration Unrecognized Tax Benefits, Reduction Resulting from Lapse of Applicable Statute of Limitations Total long-lived assets Long-Lived Assets Domestic Tax Authority Domestic Tax Authority [Member] Property and equipment, net Total property and equipment, net Property, Plant, and Equipment and Finance Lease Right-of-Use Asset, after Accumulated Depreciation and Amortization Net income Net income Net income Net Income (Loss) Attributable to Parent Schedule of Assumptions Used to Estimate the Grant Date Fair Value Employee Stock Purchase Plan Schedule of Share-Based Payment Award, Employee Stock Purchase Plan, Valuation Assumptions [Table Text Block] Matures after one year through five years Debt Securities, Available-for-Sale, Fair Value, Maturity, Allocated and Single Maturity Date, after Year One Through Five Leases Lessee, Finance Leases [Text Block] Subsequent Event Type [Axis] Subsequent Event Type [Axis] Total financial assets Assets, Fair Value Disclosure Interest income Investment Income, Interest and Dividend Vesting percentage Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Rights, Percentage Leases Lessee, Operating Leases [Text Block] Derivative Liability, Current, Statement of Financial Position [Extensible 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Other Current Liabilities [Table Text Block] Net cash provided by operating activities Net Cash Provided by (Used in) Operating Activities Gross Amounts Presented Derivative Asset Schedule of Restricted Stock and Restricted Stock Units Activity Share-Based Payment Arrangement, Restricted Stock and Restricted Stock Unit, Activity [Table Text Block] In Process Research and Development In Process Research and Development [Member] Adjustments to reconcile net income to net cash provided by operating activities: Adjustments, Noncash Items, to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Maximum percentage of annual compensation contributed by the participant (percent) Defined Contribution Plan, Maximum Annual Contributions Per Employee, Percent Forfeited (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period CRSIPR A&R JDCA CRSIPR A&R JDCA [Member] CRISPR Amended and restated the Original CTX001 JDCA Cloud computing service contracts Capitalized Computer Software, Gross Document Annual Report Document Annual Report Legal Entity [Axis] Legal Entity [Axis] Other Other Countries Outside of the United States and the United Kingdom [Member] Other Countries Outside of the United States and the United Kingdom [Member] Amount of optional renewal terms Amount of Optional Renewal Terms Amount of Optional Renewal Terms Geographical [Axis] Geographical [Axis] McKesson Corporation McKesson Corporation [Member] McKesson Corporation [Member] Cash and cash equivalents Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Cash and Equivalents Accrued expenses Increase (Decrease) in Accrued Liabilities and Other Operating Liabilities Impairment, Intangible Asset, Indefinite-Lived (Excluding Goodwill), Statement of Income or Comprehensive Income [Extensible Enumeration] Impairment, Intangible Asset, Indefinite-Lived (Excluding Goodwill), Statement of Income or Comprehensive Income [Extensible Enumeration] Other current liabilities, foreign currency forward contracts Derivative Liability, Current Collaborative Arrangement, Transaction with Party to Collaborative Arrangement Collaborative Arrangement, Transaction with Party to Collaborative Arrangement [Member] Schedule of Property and Equipment Property, Plant and Equipment [Table Text Block] Australian dollar Australia, Dollars Purchase of common stock Payment To Acquire Common Stock Payment To Acquire Common Stock Preferred stock, shares issued (in shares) Preferred Stock, Shares Issued Concentration Risk Benchmark [Domain] Concentration Risk Benchmark [Domain] Number of Shares Number of Units Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward] Jeffrey Leiden Center for Cell and Genetic Therapies Jeffrey Leiden Center for Cell and Genetic Therapies [Member] Jeffrey Leiden Center for Cell and Genetic Therapies Product and Service [Domain] Product and Service [Domain] Cash flows from operating activities: Net Cash Provided by (Used in) Operating Activities, Continuing Operations [Abstract] Entity Shell Company Entity Shell Company Common Stock, Preferred Stock and Equity Plans Common Stock, Preferred Stock and Equity Plans Disclosure [Text Block] Disclosures related to shares available for future issuance, descriptions of the stock and option plans, and the rights associated with each share. Decreases related to prior period tax positions Unrecognized Tax Benefits, Decrease Resulting from Prior Period Tax Positions Concentration Risk [Table] Concentration Risk [Table] 2023 Lessee, Operating Lease, Liability, to be Paid, Year One Financial Instrument [Axis] Financial Instrument [Axis] Deferred tax liabilities: Components of Deferred Tax Liabilities [Abstract] Right-of-use assets obtained in exchange for lease obligations Right-Of-Use Asset Obtained In Exchange For Lease Liability [Abstract] Right-Of-Use Asset Obtained In Exchange For Lease Liability [Abstract] Percent of Total Gross Product Revenues Revenue Benchmark [Member] Subsequent Event Subsequent Event [Member] Document Period End Date Document Period End Date Deferred income taxes Increase (Decrease) in Other Deferred Liability Stock options outstanding and exercisable Share-Based Payment Arrangement, Option, Exercise Price Range [Line Items] Schedule of Accumulated Other Comprehensive Income (Loss) Schedule of Accumulated Other Comprehensive Income (Loss) [Table Text Block] Total assets Assets Net income per common share: Earnings Per Share [Abstract] Discrete tax benefit associated with an intra-entity transfer of intellectual property rights Effective Income Tax Rate Reconciliation, Inter-Entity Transfer Of Intellectual Property Rights, Amount Effective Income Tax Rate Reconciliation, Inter-Entity Transfer Of Intellectual Property Rights, Amount Weighted-average assumptions for options and ESPP subscriptions granted Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions and Methodology [Abstract] Publicly Traded Companies Sale Publicly Traded Companies Sale [Member] Publicly Traded Companies Sale [Member] Lloyds Pharmacy Lloyds Pharmacy [Member] Lloyds Pharmacy Performance-based RSUs Performance Shares [Member] Fair Value Equity Securities, FV-NI, Current Antidilutive Securities [Axis] Antidilutive Securities [Axis] Credit Concentration Risk Credit Concentration Risk [Member] Exercised (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price 2027 Lessee, Operating Lease, Liability, to be Paid, Year Five Audit Information [Abstract] Audit Information [Abstract] Number of shares authorized to be repurchased Stock Repurchase Program, Authorized Amount Amounts reclassified from accumulated other comprehensive income (loss) Reclassification from AOCI, Current Period, Net of Tax, Attributable to Parent Payroll and benefits Employee-related Liabilities, Current Income before provision for income taxes Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest Earnings Per Share Earnings Per Share [Text Block] Other Deferred Tax Liabilities, Other Research, development and commercial contract costs Accrued Research Development and Commercial Contract Costs This element represents the carrying value as of the balance sheet date of obligations incurred through that date and payable for R&D and commercial of the entity. It is used to reflect the current portion of liabilities (due within one year or within the normal operating cycle, if longer). KALYDECO KALYDECO [Member] KALYDECO inventories, net Cash and Cash Equivalents Cash and Cash Equivalents, Policy [Policy Text Block] Award Type [Domain] Award Type [Domain] Potential awards, percent of target shares, minimum Share-Based Compensation By Share-Based Payment Award, Award Percentage Of Target, Minimum Share-Based Compensation By Share-Based Payment Award, Award Percentage Of Target, Minimum Duration of purchase period Share-based Compensation Arrangement by Share-based Payment Award, Duration of Purchase Period Share-based Compensation Arrangement by Share-based Payment Award, Duration of Purchase Period ORKAMBI ORKAMBI [Member] ORKAMBI [Member] Cash flows from financing activities: Net Cash Provided by (Used in) Financing Activities, Continuing Operations [Abstract] Goodwill Goodwill and Intangible Assets, Goodwill, Policy [Policy Text Block] Foreign Currency Translation Adjustment Foreign Currency Forward Contract Accumulated Foreign Currency Adjustment Attributable to Parent [Member] Entity Address, City or Town Entity Address, City or Town On Foreign Currency Forward Contracts Accumulated Gain (Loss), Net, Cash Flow Hedge, Parent [Member] Increase in unrecognized tax benefits Unrecognized Tax Benefits, Period Increase (Decrease) Tax related prepaid and receivables Tax Related Prepaid and Receivables Tax Related Prepaid and Receivables Statement of Financial Position [Abstract] Statement of Financial Position [Abstract] Cash paid for amounts included in the measurement of lease liabilities Cash Flow, Lessee [Abstract] Cash Flow, Lessee [Abstract] Raw materials Inventory, Raw Materials, Net of Reserves Auditor Name Auditor Name Market share price (in dollars per share) Share Price Operating loss carryforwards Operating Loss Carryforwards Up-front payment Collaborative Arrangement Up-front License Fee The amount of the up-front license fee paid by the entity pursuant to a collaborative arrangement. 2024 Finance Lease And Operating Lease, Liability, Payment, Due Year Two Finance Lease And Operating Lease, Liability, Payment, Due Year Two Collaborative arrangement costs Research and Development Expense Increases related to prior period tax positions Unrecognized Tax Benefits, Increase Resulting from Prior Period Tax Positions Derivative Instruments and Hedging Activities Disclosures [Table] Derivative Instruments and Hedging Activities Disclosures [Table] 2013 Stock and Option Plan Stock and Option Plan 2013 [Member] Stock and Option Plan 2013 [Member] Restricted cash and cash equivalents Restricted Cash and Cash Equivalents Restricted stock units (including PSUs) Unvested restricted stock units (including PSUs) Restricted Stock Units (excluding PSUs) Restricted Stock Units (RSUs) [Member] Discrete tax benefit associated with tax credit research Effective Income Tax Rate Reconciliation, Tax Credit, Research, Amount Cash equivalents: Cash and Cash Equivalents, Fair Value Disclosure Additional shares authorized (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Additional Shares Authorized State Deferred State and Local Income Tax Expense (Benefit) Amortized Cost Debt and Equity Securities, Cost Debt and Equity Securities, Cost Cash paid for interest Interest Paid, Excluding Capitalized Interest, Operating Activities Collaborative Arrangements by Agreement [Axis] Collaborative Arrangements by Agreement [Axis] Significant terms of collaboration arrangements, by individual agreement. Share Repurchase Program 2019 Share Repurchase Program 2019 [Member] Share Repurchase Program [Member] 2025 Lessee, Operating Lease, Liability, to be Paid, Year Three Other assets Other Assets [Member] Inventories Inventory, Policy [Policy Text Block] Concentration Risk Type [Domain] Concentration Risk Type [Domain] Counterparty Name [Domain] Counterparty Name [Domain] Total shareholders’ equity Beginning balance Ending balance Stockholders' Equity Attributable to Parent Hedging Derivative Instruments and Hedging Activities Disclosure [Text Block] Tax credit carryforwards Tax Credit Carryforward, Amount Finance leases Right-of-Use Asset Obtained in Exchange for Finance Lease Liability Cancelled (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value Vesting [Domain] Vesting [Domain] Line of Credit Facility [Line Items] Line of Credit Facility [Line Items] Tax credit carryforwards Deferred Tax Assets, Tax Credit Carryforwards Other Deferred Tax Assets, Other Number of approved medicines Number of Approved Medicines Number of Approved Medicines Government-sponsored enterprise securities Government-sponsored enterprise securities US Government-sponsored Enterprises Debt Securities [Member] San Diego Lease San Diego Lease [Member] San Diego Lease [Member] Retained Earnings (Accumulated Deficit) Retained Earnings [Member] Net lease cost Lease, Cost Common Stock Common Stock [Member] Schedule of Lease Cost Lease, Cost [Table Text Block] Additional awards authorized for grant (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant Balance at December 31, 2021 Balance at December 31, 2022 Business Combination, Contingent Consideration, Liability Statement [Table] Statement [Table] Vested (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value Letter of Credit Letter of Credit [Member] Long-term operating lease liabilities Operating Lease, Liability, Noncurrent Defined contribution plan, cost Defined Contribution Plan, Cost Statistical Measurement [Axis] Statistical Measurement [Axis] Reclassification out of Accumulated Other Comprehensive Income [Domain] Reclassification out of Accumulated Other Comprehensive Income [Domain] Leasehold improvements Leasehold Improvements [Member] Schedule of Additional Cash Flow Information Condensed Cash Flow Statement [Table Text Block] Accounts receivable, net Accounts Receivable, after Allowance for Credit Loss, Current Equity Components [Axis] Equity Components [Axis] Comprehensive Income Comprehensive Income, Policy [Policy Text Block] Expired (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Expirations in Period, Weighted Average Exercise Price Schedule of Stock and Stock Equity Plans Schedule of Stock and Stock Option, Equity Plans [Table Text Block] This schedule discloses the information pertaining to stock and stock option plans relating to the entity's equity. United Kingdom UNITED KINGDOM 2023 Finance Lease And Operating Lease, Liability, Payment, Due Next Twelve Months Finance Lease And Operating Lease, Liability, Payment, Due Next Twelve Months Statement [Line Items] Statement [Line Items] Statement [Line Items] Fair value of cash flow hedges Cash Flow Hedge Derivative Instrument Assets at Fair Value Beginning of the period (in shares) End of the period (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number Restricted Cash and Cash Equivalents Items [Line Items] Restricted Cash and Cash Equivalents Items [Line Items] Variable Rate [Domain] Variable Rate [Domain] Collaborative arrangement, milestone payment Collaborative Arrangement, Milestone Payment Collaborative Arrangement, Milestone Payment Selling, general and administrative expenses Selling, General and Administrative Expense Change in fair value of contingent consideration (Decrease) increase in fair value of contingent consideration Decrease in fair value of contingent payments Business Combination, Contingent Consideration Arrangements, Change in Amount of Contingent Consideration, Liability Royalty payable Accrued Royalties, Current Gross Unrealized Losses Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax Operating lease assets Total operating lease assets Operating Lease, Right-of-Use Asset Repurchases of common stock Repurchases of common stock Stock Repurchased During Period, Value Accumulated Other Comprehensive Income (Loss) Total AOCI Attributable to Parent [Member] Accumulated Other Comprehensive Income (Loss) Comprehensive Income (Loss) Note [Text Block] Mammoth Biosciences, Inc Mammoth Biosciences, Inc [Member] Mammoth Biosciences, Inc Auditor Firm ID Auditor Firm ID Finance Lease, Liability, Current, Statement of Financial Position [Extensible List] Finance Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration] Document Transition Report Document Transition Report Foreign Tax Authority Foreign Tax Authority [Member] Local Phone Number Local Phone Number Schedule of Outstanding and Vested Options Share-Based Payment Arrangement, Option, Activity [Table Text Block] Income from operations Operating Income (Loss) Recently Adopted and Issued Accounting Standards New Accounting Pronouncements, Policy [Policy Text Block] Effect of potentially dilutive securities: Weighted Average Number of Shares Outstanding, Diluted, Adjustment [Abstract] Prepaid expenses and other assets Increase (Decrease) in Prepaid Expense and Other Assets State and Local Jurisdiction State and Local Jurisdiction [Member] Gross Unrealized Losses Equity Securities, FV-NI, Unrealized Loss Repurchases of common stock (in shares) Repurchases of common stock (in shares) Stock Repurchased During Period, Shares Indefinite-lived intangible assets acquired Indefinite-Lived Intangible Assets Acquired Name of Property [Domain] Name of Property [Domain] Awards outstanding (in shares) Share-Based Compensation Arrangement By Share-based Payment Award, Equity Instruments Outstanding, Number Share-Based Compensation Arrangement By Share-based Payment Award, Equity Instruments Outstanding, Number Intangible Assets and Goodwill Goodwill and Intangible Assets Disclosure [Text Block] Finance Lease, Right-of-Use Asset, Statement of Financial Position [Extensible List] Finance Lease, Right-of-Use Asset, Statement of Financial Position [Extensible Enumeration] 2027 Finance Lease And Operating Lease, Liability, Payments, Due Year Five Finance Lease And Operating Lease, Liability, Payments, Due Year Five Collaborative Arrangement and Arrangement Other than Collaborative [Table] Collaborative Arrangement and Arrangement Other than Collaborative [Table] Property and Equipment Property, Plant and Equipment, Policy [Policy Text Block] Preferred stock, par value (in dollars per share) Preferred Stock, Par or Stated Value Per Share 2026 Lessee, Operating Lease, Liability, to be Paid, Year Four Fair Value Cash Equivalents And Debt Securities, Available for Sale, Fair Value Disclosure Cash Equivalents And Debt Securities, Available for Sale, Fair Value Disclosure Income Statement [Abstract] Income Statement [Abstract] Federal Deferred Federal Income Tax Expense (Benefit) Additional Paid-in Capital Additional Paid-in Capital [Member] Document Fiscal Period Focus Document Fiscal Period Focus Total intrinsic value of stock options exercised Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value Derivative [Line Items] Derivative [Line Items] Diluted (in shares) Diluted weighted-average common shares outstanding (in shares) Weighted Average Number of Shares Outstanding, Diluted Schedule of Inventories by Type Schedule of Inventory, Current [Table Text Block] Schedule of Weighted-Average Remaining Lease Terms and Discount Rates Schedule of Weighted-Average Remaining Lease Terms and Discount Rates Related to Leases [Table Text Block] Schedule of Weighted-Average Remaining Lease Terms and Discount Rates Related to Leases [Table Text Block] Expected term of options (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term Debt Securities, Available-for-sale [Line Items] Debt Securities, Available-for-Sale [Line Items] Buildings and improvements Building and Building Improvements [Member] ICFR Auditor Attestation Flag ICFR Auditor Attestation Flag Base Rate Base Rate [Member] Marketable securities: Marketable Securities Weighted-average Remaining Contractual Life Weighted Average, Remaining Contractual Life [Abstract] -- None. No documentation exists for this element. -- Schedule of Supplemental Cash Flow Information Lease, Supplemental Cash Flow Information [Table Text Block] Lease, Supplemental Cash Flow Information [Table Text Block] Granted (in dollars per share) Granted (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value Schedule of Financial Assets Subject to Fair Value Measurements Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block] Proceeds from finance leases Proceeds From Finance Leases Proceeds From Finance Leases Exercisable Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value Financial instruments carried at fair value (liability positions): Financial Liabilities Fair Value Disclosure [Abstract] Preferred stock, shares authorized (in shares) Preferred Stock, Shares Authorized Product Concentration Risk Product Concentration Risk [Member] Decrease in unrecognized tax benefits is reasonably possible Decrease in Unrecognized Tax Benefits is Reasonably Possible Foreign currency forward contracts Foreign Exchange Forward [Member] Schedule of PSU Activity Share-Based Payment Arrangement, Performance Shares, Outstanding Activity [Table Text Block] Common stock, shares issued (in shares) Common Stock, Shares, Issued Concentration Risk [Line Items] Concentration Risk [Line Items] Net foreign currency transaction loss Foreign Currency Transaction Gain (Loss), before Tax Schedule of Sale of Equity Investments Debt Securities, Trading, and Equity Securities, FV-NI [Table Text Block] Finance lease liabilities Finance Lease, Liability, Current Cash Flow Hedging Cash Flow Hedging [Member] Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Total liabilities Offsetting Derivative Liabilities [Abstract] Net cash (used in) provided by investing activities Net Cash Provided by (Used in) Investing Activities Comprehensive income Comprehensive Income (Loss), Net of Tax, Attributable to Parent Issuances of common stock under benefit plans Proceeds, Issuance of Shares, Share-Based Payment Arrangement, Including Option Exercised Entity Current Reporting Status Entity Current Reporting Status Other current liabilities Total Other Liabilities, Current $150.01–$200.00 Exercise Price Range from Dollars 150.01 to Dollars 200.00 [Member] Represents the range of exercise prices from $150.01 to $200.00 per share for the purpose of disclosing shares potentially issuable under outstanding stock options, as well as other option information. Weighted-average remaining lease term (in years) Weighted-Average Remaining Lease [Abstract] Weighted-Average Remaining Lease [Abstract] 2023 Finance Lease, Liability, to be Paid, Year One Federal statutory tax rate Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent $100.01–$150.00 Exercise Price Range from Dollars 100.01 to Dollars 150.00 [Member] Represents the range of exercise prices from $100.01 to $150.00 per share for the purpose of disclosing shares potentially issuable under outstanding stock options, as well as other option information. Number of shares (in shares) Stock Issued During Period, Shares, Employee Stock Purchase Plans Schedule of Assets Acquired and Liabilities Assumed Schedule of Recognized Identified Assets Acquired and Liabilities Assumed [Table Text Block] Derivative [Table] Derivative [Table] Outstanding at beginning of period (in shares) Outstanding at end of period (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number Stock compensation (benefit), shortfalls and cancellations Effective Income Tax Rate Reconciliation, Nondeductible Expense, Share-Based Payment Arrangement, Percent State taxes, net of federal benefit Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Percent 2024 Finance Lease, Liability, to be Paid, Year Two Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] Basis of Presentation Basis of Accounting, Policy [Policy Text Block] Effect of changes in exchange rates on cash Effect of Exchange Rate on Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Continuing Operations Cancelled (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period Other (expense) income, net Other Nonoperating Income (Expense) Balance Sheet Location [Axis] Balance Sheet Location [Axis] Nature of Business and Accounting Policies Organization, Consolidation, Basis of Presentation, Business Description and Accounting Policies [Text Block] Other long-term liabilities, contingent consideration Contingent consideration Business Combination, Contingent Consideration, Liability, Noncurrent Swiss Franc Switzerland, Francs Derivative Instruments and Hedging Activities Disclosures [Line Items] Derivative Instruments and Hedging Activities Disclosures [Line Items] Revenues by Product Revenue from External Customers by Products and Services [Table Text Block] Accumulated other comprehensive income Accumulated Other Comprehensive Income (Loss), Net of Tax CRISPR CRISPR [Member] CRISPR Total current assets Assets, Current Tax related accruals Taxes Payable, Current Cash paid for income taxes Income Taxes Paid, Net Revenues related to performance obligations Contract with Customer, Liability, Revenue Recognized Entity Small Business Entity Small Business Present value of lease liabilities Finance Lease And Operating Lease, Liability Finance Lease And Operating Lease, Liability Share Repurchase Programs Stockholders' Equity, Policy [Policy Text Block] Unrecognized Expense Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount Stock Options Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward] Significant Customers Schedules of Concentration of Risk, by Risk Factor [Table Text Block] Property and Equipment Property, Plant and Equipment Disclosure [Text Block] Outstanding Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value $45.11–$100.00 Exercise Price Range from Dollars 45.11 to Dollars 100.00 [Member] Represents the range of exercise prices from $36.28 to $100.00 per share for the purpose of disclosing shares potentially issuable under outstanding stock options, as well as other option information. Property, Plant and Equipment, Type [Domain] Long-Lived Tangible Asset [Domain] Long-Lived Tangible Asset [Domain] Summary of Other Long Term Liabilities Other Noncurrent Liabilities [Table Text Block] U.S. tax on foreign earnings, net of credits Effective Income Tax Rate Reconciliation, Repatriation of Foreign Earnings, Percent Total costs and expenses Costs and Expenses Marketable securities and other assets Marketable Securities And Other Noncurrent Assets [Member] Marketable Securities And Other Noncurrent Assets Granted (in shares) Stock options granted (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Net of Forfeitures Business Combination and Asset Acquisition [Abstract] Present value of lease liabilities Present value of lease liabilities Operating Lease, Liability Tax related liabilities Tax Related Liabilities, Noncurrent Tax Related Liabilities, Noncurrent Total lease payments Finance Lease, Liability, to be Paid Schedule of Finance Lease, Liability, Maturity Finance Lease, Liability, Fiscal Year Maturity [Table Text Block] Investments, Debt and Equity Securities [Abstract] Investments, Debt and Equity Securities [Abstract] Option to extend lease term Lessee, Finance Lease, Term of Contract Granted (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Amortized Cost Debt Securities, Available-for-Sale, Amortized Cost Schedule of Shares Issued Under Employee Stock Purchase Plan Schedule of Share-Based Compensation, Employee Stock Purchase Plan, Activity [Table Text Block] Tax Carryforwards [Line Items] Tax Carryforwards [Line Items] -- None. No documentation exists for this element. -- CRISPR Therapeutics CRISPR Therapeutics AG [Member] CRISPR Therapeutics AG Allocation of net profits and net losses, percent Collaborative Arrangement, Allocation Of Net Profits And Losses, Percent Collaborative Arrangement, Allocation Of Net Profits And Losses, Percent Hedging Relationship [Domain] Hedging Relationship [Domain] Hedging Designation [Axis] Hedging Designation [Axis] Auditor Location Auditor Location Entity Filer Category Entity Filer Category Gross Amounts Offset Derivative Asset, Subject to Master Netting Arrangement, Liability Offset Shareholders’ equity: Stockholders' Equity, Including Portion Attributable to Noncontrolling Interest [Abstract] Federal Current Federal Tax Expense (Benefit) United States United States UNITED STATES Eligible employee purchase price percentage of fair value Share-based Compensation Arrangement by Share-based Payment Award, Eligible Employee Purchase Price Percentage of Fair Value This element represents the percentage of the fair market value of the entity's common stock on the first day of the applicable offering period or last day of the applicable purchase period that eligible employees may purchase shares of the entity's common stock under the employee stock purchase plan. Asset acquisition, consideration transferred Asset Acquisition, Consideration Transferred Stock-based compensation expense related to inventories Share-Based Payment Arrangement, Expense Commitments and contingencies Commitments and Contingencies Security Exchange Name Security Exchange Name Outstanding at beginning of period (in dollars per share) Outstanding at end of period (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price Weighted-average 
Grant-date Fair Value Weighted-average 
Grant-date Fair Value Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Additional Disclosures [Abstract] TRIKAFTA/KAFTRIO TRIKAFTA/KAFTRIO [Member] TRIKAFTA/KAFTRIO Revenue Product revenues, net Total product revenues, net Revenue from Contract with Customer, Excluding Assessed Tax Other Other Countries Outside of the United States and Europe [Member] Other Countries Outside of the United States and Europe [Member] Cash and cash equivalents Cash and Cash Equivalents [Member] Cover [Abstract] Cover [Abstract] Entity Voluntary Filers Entity Voluntary Filers Tax credits Effective Income Tax Rate Reconciliation, Tax Credit, Percent Finance leases Finance Lease, Weighted Average Discount Rate, Percent Segment Reporting [Abstract] Segment Reporting [Abstract] Number of installments Share-based Compensation Arrangement By Share-based Payment Award, Number Of Installments Share-based Compensation Arrangement By Share-based Payment Award, Number Of Installments Derivative asset current, foreign currency forward contracts Derivative Asset, Current Risk-free interest rate (percent) Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate Documents Incorporated by Reference Documents Incorporated by Reference [Text Block] Payments in connection with common stock withheld for employee tax obligations Payment, Tax Withholding, Share-Based Payment Arrangement Total liabilities and shareholders’ equity Liabilities and Equity Number of shares remaining for repurchases Stock Repurchase Program, Remaining Authorized Repurchase Amount Cash Cash Gross deferred tax assets Deferred Tax Assets, Gross Not designated as hedging instrument Not Designated as Hedging Instrument [Member] Lease agreements number of buildings Lease Agreements Number of Buildings Represents number of buildings under lease agreements. Schedule of Components of Income Before Provision for (Benefit From) Income Taxes Schedule of Income before Income Tax, Domestic and Foreign [Table Text Block] Thereafter Finance Lease And Operating Lease, Liability, Payments, Due After Year Five Finance Lease And Operating Lease, Liability, Payments, Due After Year Five Unrecognized tax benefits, income tax penalties and interest accrued Unrecognized Tax Benefits, Income Tax Penalties and Interest Accrued Less: amount representing interest Lessee, Operating Lease, Liability, Undiscounted Excess Amount Vesting [Axis] Vesting [Axis] Diluted (in dollars per share) Diluted net income per common share (in dollars per share) Earnings Per Share, Diluted Vesting period Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period Gross Amounts Not Offset Derivative Liability, Subject to Master Netting Arrangement, Deduction of Financial Instrument Not Offset Share-based Payment Arrangement, Additional Disclosure [Abstract] Share-Based Payment Arrangement, Additional Disclosure [Abstract] Exercise Price Range [Domain] Exercise Price Range [Domain] 2024 Lessee, Operating Lease, Liability, to be Paid, Year Two Other Other Assets, Current Total stock-based compensation expense included in costs and expenses Share-Based Payment Arrangement, Expensed and Capitalized, Amount Foreign currency translation adjustment Unrecognized Tax Benefits, Decrease Resulting from Foreign Currency Translation Total deferred tax assets Deferred Tax Assets, Net of Valuation Allowance Unrecognized tax benefits Balance at beginning of the period Balance at end of period Unrecognized Tax Benefits Acquired intangibles Deferred Tax Liabilities, Intangible Assets Corporate equity securities Equity Securities [Member] Share Repurchase Program [Axis] Share Repurchase Program [Axis] United States Income (Loss) from Continuing Operations before Income Taxes, Domestic Corporate debt securities Corporate debt securities Corporate Debt Securities [Member] Gross Amounts Offset Derivative Liability, Subject to Master Netting Arrangement, Asset Offset Equity, Class of Treasury Stock [Line Items] Equity, Class of Treasury Stock [Line Items] Total assets Gross Amounts Recognized Derivative Asset, Subject to Master Netting Arrangement, before Offset Schedule of Operating Lease, Liability, Maturity Lessee, Operating Lease, Liability, Maturity [Table Text Block] Entity Address, Address Line One Entity Address, Address Line One Stock-based compensation expense related to inventories Share-Based Payment Arrangement, Amount Capitalized Contract liabilities Contract with Customer, Liability Product and Service [Axis] Product and Service [Axis] Tax rate change Effective Income Tax Rate Reconciliation, Change in Enacted Tax Rate, Percent Total marketable debt securities Debt Securities, Available-for-Sale [Abstract] Summary of Accrued Expenses Schedule of Accrued Liabilities [Table Text Block] Inventories Inventory Disclosure [Text Block] Operating lease liabilities Deferred Tax Liabilities, Leasing Arrangements Buildings and improvements Building [Member] Inventory Disclosure [Abstract] Inventory Disclosure [Abstract] Other assets Other Noncurrent Assets [Member] Performance period Share-Based Compensation by Share-Based Payment Award, Performance Period Share-Based Compensation by Share-Based Payment Award, Performance Period Gross Unrealized Losses Debt and Equity Securities, Unrealized Loss Debt and Equity Securities, Unrealized Loss Total deferred tax liabilities Deferred Tax Liabilities, Gross Revenues: Revenue from Contract with Customer [Abstract] Total property and equipment, gross Property, Plant, and Equipment and Finance Lease Right-of-Use Asset, before Accumulated Depreciation and Amortization Operating cash flows from finance leases Finance Lease, Interest Payment on Liability Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward] Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward] Total product revenues outside of the United States Total long-lived assets outside of the United States Outside the United States [Member] Outside the United States [Member] Commercial paper Commercial paper Commercial Paper [Member] Fair Value by Measurement Frequency [Axis] Measurement Frequency [Axis] Name of Property [Axis] Name of Property [Axis] Other Other Accrued Liabilities, Current Options exercisable, weighted-average exercise price (in dollars per share) Share-Based Payment Arrangement, Option, Exercise Price Range, Exercisable, Weighted Average Exercise Price Collaborative arrangement, right to exclusively license, number of targets Collaborative Arrangement, Right To License, Number Of Targets Collaborative Arrangement, Right To License, Number Of Targets Euro Euro Member Countries, Euro Statement of Stockholders' Equity [Abstract] Statement of Stockholders' Equity [Abstract] Schedule of Reconciliation of the Provision for (Benefit From) Income Taxes Income Tax Expense (Benefit) Continuing Operations, Income Tax Reconciliation [Table Text Block] This block of text may be used to disclose all or parts of the required information for reconciliation of income tax provisions. Acquired in-process research and development expenses Research and Development in Process Less: amount representing interest Finance Lease, Liability, Undiscounted Excess Amount Derivative Liability, Noncurrent, Statement of Financial Position [Extensible Enumeration] Derivative Liability, Noncurrent, Statement of Financial Position [Extensible Enumeration] Research and development expenses Research and Development Expense [Member] Cost of sales Cost of Sales [Member] Offering period (in months) Share-based Compensation Arrangement by Share-based Payment Award, Offering Period Share-based Compensation Arrangement by Share-based Payment Award, Offering Period Aggregate Intrinsic Value Aggregate intrinsic value [Abstract] -- None. No documentation exists for this element. -- Other long-term liabilities, foreign currency forward contracts Derivative Liability, Noncurrent