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Oct 16, 2008

Vertex Pharmaceuticals Announces the Date of its Third Quarter 2008 Financial Results Conference Call and Webcast

CAMBRIDGE, Mass., Oct 16, 2008 (BUSINESS WIRE) -- Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) will announce its third quarter 2008 financial results on Monday, October 27, 2008 after the financial markets close. The Company will host a conference call at 5:00 p.m. EDT.

The conference call will be webcast live and may be accessed from the 'Events & Presentations' page of Vertex's website at www.vrtx.com. A replay of the conference call and webcast will be archived on the Company's website until November 10, 2008. To ensure a timely connection, it is recommended that users register at least 15 minutes prior to the scheduled webcast.

About Vertex

Vertex Pharmaceuticals Incorporated is a global biotechnology company committed to the discovery and development of breakthrough small molecule drugs for serious diseases. The Company's strategy is to commercialize its products both independently and in collaboration with major pharmaceutical companies. Vertex's product pipeline is focused on viral diseases, inflammation, autoimmune diseases, cancer, pain and cystic fibrosis. Vertex co-discovered the HIV protease inhibitor, Lexiva, with GlaxoSmithKline.

Lexiva is a registered trademark of the GlaxoSmithKline group of companies.

Vertex's press releases are available at www.vrtx.com.

VRTX-WEB

SOURCE: Vertex Pharmaceuticals Incorporated

Vertex 
Lora Pike, 617-444-6755 
Manager, Investor Relations

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